Investigation of Interaction between the Spike Protein of SARS-CoV-2 and ACE2-Expressing Cells Using an In Vitro Cell Capturing System

Investigation of Interaction between the Spike Protein of SARS-CoV-2 and ACE2-Expressing Cells Using an In Vitro Cell Capturing System

Abstract Background The Interaction between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein with Angiotensin converting enzyme 2 (ACE2) on the host cells is a crucial step for the viral entry and infection. Therefore, investigating the molecular mechanism underlying the in...

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Bibliographic Details
Main Authors: Yuning Shang, Feixiang Chen, Shasha Li, Lijuan Song, Yunzhen Gao, Xinhua Yu, Junfeng Zheng
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Biological Procedures Online
Subjects:
SARS-CoV-2;spike protein
ACE2
In vitro cell-capture
Online Access:https://doi.org/10.1186/s12575-021-00153-9

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