Optical coherence tomography-based assessment of central macular thickness after penetrating keratoplasty
Purpose: To assess the pattern of change in central macular thickness (CMT) after penetrating keratoplasty (PKP) with the help of optical coherence tomography (OCT) and to know the prevalence and prognosis of cystoid macular edema (CME) in these patients. Materials and Methods: A hospital-based pros...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | TNOA Journal of Ophthalmic Science and Research |
| Subjects: | |
| Online Access: | http://www.tnoajosr.com/article.asp?issn=2589-4528;year=2017;volume=55;issue=4;spage=278;epage=281;aulast=Singh |
| _version_ | 1818219081088630784 |
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| author | Mamta Singh Bibhuti P Sinha |
| author_facet | Mamta Singh Bibhuti P Sinha |
| author_sort | Mamta Singh |
| collection | DOAJ |
| description | Purpose: To assess the pattern of change in central macular thickness (CMT) after penetrating keratoplasty (PKP) with the help of optical coherence tomography (OCT) and to know the prevalence and prognosis of cystoid macular edema (CME) in these patients. Materials and Methods: A hospital-based prospective study of 13 eyes of 13 patients of PKP was conducted. Eleven of them underwent PKP and two of them underwent triple procedure. Postoperative CMT analysis was done with OCT at the end of 1st, 2nd, and 3rd month. CME has been defined as CMT >250 μ, loss of normal foveal contour, and cystoid changes in the central macula. Patients with macular edema were continued with the routine postoperative regimen of PKP. Results: The CMT at the end of 1, 2, and 3 months were 253.46 ± 37.50 μ, 230 ± 34.89 μ, and 214.53 ± 33.84 μ, respectively. The statistical difference between 1st and 2nd month and between 2nd and 3rd month was very significant. The prevalence of CME at the end of 1st, 2nd, and 3rd month was 30.7%, 23.07%, and 7.69% respectively. At month 1, 42.85% cases of pseudophakic bullous keratopathy and 16.66% cases of corneal opacity patients had CME. Triple procedure is associated with higher CMT in comparison to simple keratoplasty, but this difference was not significant statistically. Conclusion: There is a gradual decline in CMT and prevalence of macular edema with time. Hence, not every case of diagnosed macular edema after PKP needs to be treated very aggressively. Triple procedure without vitreous manipulations has no separate implication on incidence of CME, than a routine PKP. |
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| format | Article |
| id | doaj.art-4db984121e484f11832b474e1d1c5994 |
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| issn | 2589-4528 2589-4536 |
| language | English |
| last_indexed | 2024-12-12T07:33:59Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
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| series | TNOA Journal of Ophthalmic Science and Research |
| spelling | doaj.art-4db984121e484f11832b474e1d1c59942022-12-22T00:32:57ZengWolters Kluwer Medknow PublicationsTNOA Journal of Ophthalmic Science and Research2589-45282589-45362017-01-0155427828110.4103/tjosr.tjosr_3_18Optical coherence tomography-based assessment of central macular thickness after penetrating keratoplastyMamta SinghBibhuti P SinhaPurpose: To assess the pattern of change in central macular thickness (CMT) after penetrating keratoplasty (PKP) with the help of optical coherence tomography (OCT) and to know the prevalence and prognosis of cystoid macular edema (CME) in these patients. Materials and Methods: A hospital-based prospective study of 13 eyes of 13 patients of PKP was conducted. Eleven of them underwent PKP and two of them underwent triple procedure. Postoperative CMT analysis was done with OCT at the end of 1st, 2nd, and 3rd month. CME has been defined as CMT >250 μ, loss of normal foveal contour, and cystoid changes in the central macula. Patients with macular edema were continued with the routine postoperative regimen of PKP. Results: The CMT at the end of 1, 2, and 3 months were 253.46 ± 37.50 μ, 230 ± 34.89 μ, and 214.53 ± 33.84 μ, respectively. The statistical difference between 1st and 2nd month and between 2nd and 3rd month was very significant. The prevalence of CME at the end of 1st, 2nd, and 3rd month was 30.7%, 23.07%, and 7.69% respectively. At month 1, 42.85% cases of pseudophakic bullous keratopathy and 16.66% cases of corneal opacity patients had CME. Triple procedure is associated with higher CMT in comparison to simple keratoplasty, but this difference was not significant statistically. Conclusion: There is a gradual decline in CMT and prevalence of macular edema with time. Hence, not every case of diagnosed macular edema after PKP needs to be treated very aggressively. Triple procedure without vitreous manipulations has no separate implication on incidence of CME, than a routine PKP.http://www.tnoajosr.com/article.asp?issn=2589-4528;year=2017;volume=55;issue=4;spage=278;epage=281;aulast=Singhcentral macular thicknessoptical coherence tomographypenetrating keratoplasty |
| spellingShingle | Mamta Singh Bibhuti P Sinha Optical coherence tomography-based assessment of central macular thickness after penetrating keratoplasty TNOA Journal of Ophthalmic Science and Research central macular thickness optical coherence tomography penetrating keratoplasty |
| title | Optical coherence tomography-based assessment of central macular thickness after penetrating keratoplasty |
| title_full | Optical coherence tomography-based assessment of central macular thickness after penetrating keratoplasty |
| title_fullStr | Optical coherence tomography-based assessment of central macular thickness after penetrating keratoplasty |
| title_full_unstemmed | Optical coherence tomography-based assessment of central macular thickness after penetrating keratoplasty |
| title_short | Optical coherence tomography-based assessment of central macular thickness after penetrating keratoplasty |
| title_sort | optical coherence tomography based assessment of central macular thickness after penetrating keratoplasty |
| topic | central macular thickness optical coherence tomography penetrating keratoplasty |
| url | http://www.tnoajosr.com/article.asp?issn=2589-4528;year=2017;volume=55;issue=4;spage=278;epage=281;aulast=Singh |
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