As a prognostic biomarker of clear cell renal cell carcinoma RUFY4 predicts immunotherapy responsiveness in a PDL1-related manner

As a prognostic biomarker of clear cell renal cell carcinoma RUFY4 predicts immunotherapy responsiveness in a PDL1-related manner

Abstract Background Clear cell renal cell carcinoma (ccRCC) is one of the most lethal malignancies in the urinary system and the existing immunotherapy has not achieved satisfactory outcomes. Therefore, this study aims at establishing a novel gene signature for immune infiltration and clinical outco...

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Bibliographic Details
Main Authors: Daojia Miao, Jian Shi, Zhiyong Xiong, Wen Xiao, Xiangui Meng, Qingyang Lv, Kairu Xie, Hongmei Yang, Xiaoping Zhang
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Cancer Cell International
Subjects:
Clear cell renal cell carcinoma
Immune infiltration
Immunotherapy
PD-1 blockade
Prognostic signatures
Online Access:https://doi.org/10.1186/s12935-022-02480-7

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