TC14012 enhances the anti-fibrosis effects of UC-MSCs on the liver by reducing collagen accumulation and ameliorating inflammation

TC14012 enhances the anti-fibrosis effects of UC-MSCs on the liver by reducing collagen accumulation and ameliorating inflammation

Abstract Background Mesenchymal stem cells (MSCs) are attracting attention as a promising cell-based therapy for the treatment of liver fibrosis or cirrhosis. However, the strategies and potential mechanisms of MSCs therapy need further investigation. The CXCL12/CXCR4/CXCR7 chemokine axis is well kn...

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Bibliographic Details
Main Authors: Fan Ding, Yuting Liu, Jia Li, Xiao Wei, Jiangdong Zhao, Xiaojing Liu, Liqiang Zhang
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Stem Cell Research & Therapy
Subjects:
Liver fibrosis
UC-MSCs
TC14012
LSEC
HSCs
Immunoregulation
Online Access:https://doi.org/10.1186/s13287-024-03648-w

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