Cherubism
Cherubism is a rare non-neoplastic fibro-osseous disorder characterized by clinically evident bilateral painless enlargement of the jaws that usually gives a cherubic appearance. Cherubism is due to dominant mutations in the SH3-binding protein 2 (SH3BP2) gene on chromosome 4p16.3.The skeletal defor...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | SRM Journal of Research in Dental Sciences |
| Subjects: | |
| Online Access: | http://www.srmjrds.in/article.asp?issn=0976-433X;year=2017;volume=8;issue=2;spage=82;epage=84;aulast=Farooqui |
| _version_ | 1811196508814442496 |
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| author | Anjum Farooqui Yogita Khalekar Jamebashher Farooqui Amit Zope |
| author_facet | Anjum Farooqui Yogita Khalekar Jamebashher Farooqui Amit Zope |
| author_sort | Anjum Farooqui |
| collection | DOAJ |
| description | Cherubism is a rare non-neoplastic fibro-osseous disorder characterized by clinically evident bilateral painless enlargement of the jaws that usually gives a cherubic appearance. Cherubism is due to dominant mutations in the SH3-binding protein 2 (SH3BP2) gene on chromosome 4p16.3.The skeletal deformity causes dental complications. Bilateral swelling of the jaws usually appears between the age of 2 and 7 years, after which, the lesions proliferate and increase in size until puberty. These lesions subsequently begin to regress, fill with bone and remodel until the age of 30 years. Here we present a case of 20 years male patient with cherubism. |
| first_indexed | 2024-04-12T00:58:58Z |
| format | Article |
| id | doaj.art-4dc39ba5386b4b3ebfde2bfabd137a2a |
| institution | Directory Open Access Journal |
| issn | 2772-5243 2772-5251 |
| language | English |
| last_indexed | 2024-04-12T00:58:58Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | SRM Journal of Research in Dental Sciences |
| spelling | doaj.art-4dc39ba5386b4b3ebfde2bfabd137a2a2022-12-22T03:54:31ZengWolters Kluwer Medknow PublicationsSRM Journal of Research in Dental Sciences2772-52432772-52512017-01-0182828410.4103/srmjrds.srmjrds_55_16CherubismAnjum FarooquiYogita KhalekarJamebashher FarooquiAmit ZopeCherubism is a rare non-neoplastic fibro-osseous disorder characterized by clinically evident bilateral painless enlargement of the jaws that usually gives a cherubic appearance. Cherubism is due to dominant mutations in the SH3-binding protein 2 (SH3BP2) gene on chromosome 4p16.3.The skeletal deformity causes dental complications. Bilateral swelling of the jaws usually appears between the age of 2 and 7 years, after which, the lesions proliferate and increase in size until puberty. These lesions subsequently begin to regress, fill with bone and remodel until the age of 30 years. Here we present a case of 20 years male patient with cherubism.http://www.srmjrds.in/article.asp?issn=0976-433X;year=2017;volume=8;issue=2;spage=82;epage=84;aulast=Farooquicherubismchromosomedominantmutations |
| spellingShingle | Anjum Farooqui Yogita Khalekar Jamebashher Farooqui Amit Zope Cherubism SRM Journal of Research in Dental Sciences cherubism chromosome dominant mutations |
| title | Cherubism |
| title_full | Cherubism |
| title_fullStr | Cherubism |
| title_full_unstemmed | Cherubism |
| title_short | Cherubism |
| title_sort | cherubism |
| topic | cherubism chromosome dominant mutations |
| url | http://www.srmjrds.in/article.asp?issn=0976-433X;year=2017;volume=8;issue=2;spage=82;epage=84;aulast=Farooqui |
| work_keys_str_mv | AT anjumfarooqui cherubism AT yogitakhalekar cherubism AT jamebashherfarooqui cherubism AT amitzope cherubism |