Complementary effects of two growth factors in multifunctionalized silk nanofibers for nerve reconstruction.

Complementary effects of two growth factors in multifunctionalized silk nanofibers for nerve reconstruction.

With the aim of forming bioactive guides for peripheral nerve regeneration, silk fibroin was electrospun to obtain aligned nanofibers. These fibers were functionalized by incorporating Nerve Growth Factor (NGF) and Ciliary NeuroTrophic Factor (CNTF) during electrospinning. PC12 cells grown on the fi...

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Bibliographic Details
Main Authors: Tony M Dinis, Guillaume Vidal, Rodrigo R Jose, Pascale Vigneron, Damien Bresson, Vincent Fitzpatrick, Frédéric Marin, David L Kaplan, Christophe Egles
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4196919?pdf=render

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