Intraoperative Radiotherapy and Breast Cancer: Review

Intraoperative radiation therapy in breast cancer (IORT) delivers a concentrated dose of radiation therapy to a tumor bed during surgery. IORT offers some of the following advantages with typically fewer complications like; maximum effect, sparing healthy tissues and organs, to help the patients fin...

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Main Authors: Arzu Akan, Şerife Şimsek
Format: Article
Language:English
Published: Galenos Publishing House 2014-10-01
Series:European Journal of Breast Health
Subjects:
Online Access: http://www.eurjbreasthealth.com/archives/archive-detail/article-preview/ntraoperative-radiotherapy-and-breast-cancer-revie/42252
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author Arzu Akan
Şerife Şimsek
author_facet Arzu Akan
Şerife Şimsek
author_sort Arzu Akan
collection DOAJ
description Intraoperative radiation therapy in breast cancer (IORT) delivers a concentrated dose of radiation therapy to a tumor bed during surgery. IORT offers some of the following advantages with typically fewer complications like; maximum effect, sparing healthy tissues and organs, to help the patients finish treatment and get back to their normal activities. The goal of IORT is to improve local tumor control and survival rates for patients with breast cancer. IORT can both be performed with electron beams (ELIOT) and Xrays. Two main randomised trials testing intraoperative partial breast radiotherapy are TARGIT trial and the ELIOT (intraoperative radiotherapy with electrons) trial, but the techniques are fundamentally different. Whereas TARGIT delivers radiation from within the undisturbed tumour bed, for ELIOT, the mammary gland is mobilised, a prepectoral lead shield is inserted, the edges of the tumour bed are apposed, and radiation is delivered from without.
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spelling doaj.art-4dc6fdfc7578427489f78c9a83d2bd462023-02-15T16:20:00ZengGalenos Publishing HouseEuropean Journal of Breast Health2587-08312014-10-0110419019610.5152/tjbh.2014.211713049054Intraoperative Radiotherapy and Breast Cancer: ReviewArzu Akan0Şerife Şimsek1 Genel Cerrahi Kliniği, Okmeydanı Eğitim ve Araştırma Hastanesi, İstanbul, Türkiye EMSEY Hastanesi, Meme Cerrahisi kliniği, İstanbul, Türkiye Intraoperative radiation therapy in breast cancer (IORT) delivers a concentrated dose of radiation therapy to a tumor bed during surgery. IORT offers some of the following advantages with typically fewer complications like; maximum effect, sparing healthy tissues and organs, to help the patients finish treatment and get back to their normal activities. The goal of IORT is to improve local tumor control and survival rates for patients with breast cancer. IORT can both be performed with electron beams (ELIOT) and Xrays. Two main randomised trials testing intraoperative partial breast radiotherapy are TARGIT trial and the ELIOT (intraoperative radiotherapy with electrons) trial, but the techniques are fundamentally different. Whereas TARGIT delivers radiation from within the undisturbed tumour bed, for ELIOT, the mammary gland is mobilised, a prepectoral lead shield is inserted, the edges of the tumour bed are apposed, and radiation is delivered from without. http://www.eurjbreasthealth.com/archives/archive-detail/article-preview/ntraoperative-radiotherapy-and-breast-cancer-revie/42252 intraoperative periodbreast cancertreatment
spellingShingle Arzu Akan
Şerife Şimsek
Intraoperative Radiotherapy and Breast Cancer: Review
European Journal of Breast Health
intraoperative period
breast cancer
treatment
title Intraoperative Radiotherapy and Breast Cancer: Review
title_full Intraoperative Radiotherapy and Breast Cancer: Review
title_fullStr Intraoperative Radiotherapy and Breast Cancer: Review
title_full_unstemmed Intraoperative Radiotherapy and Breast Cancer: Review
title_short Intraoperative Radiotherapy and Breast Cancer: Review
title_sort intraoperative radiotherapy and breast cancer review
topic intraoperative period
breast cancer
treatment
url http://www.eurjbreasthealth.com/archives/archive-detail/article-preview/ntraoperative-radiotherapy-and-breast-cancer-revie/42252
work_keys_str_mv AT arzuakan intraoperativeradiotherapyandbreastcancerreview
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