Cutaneous metastasis as the first manifestation of occult malignant breast neoplasia
Abstract Cutaneous metastases from primary internal malignancies represent 0.7-9% of patients with cancer. We report a 65-year-old female patient referred for evaluation of normochromic papules on the trunk and upper limbs that had been present for three months. A skin biopsy revealed diffuse cutane...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Dermatologia
2016-10-01
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| Series: | Anais Brasileiros de Dermatologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016001100105&tlng=en |
| _version_ | 1818744553779232768 |
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| author | Ellem Tatiani de Souza Weimann Erica Bruder Botero Cinthia Mendes Marcel Alex Soares dos Santos Rafael Fantelli Stelini Caroline Romanelli T. Zelenika |
| author_facet | Ellem Tatiani de Souza Weimann Erica Bruder Botero Cinthia Mendes Marcel Alex Soares dos Santos Rafael Fantelli Stelini Caroline Romanelli T. Zelenika |
| author_sort | Ellem Tatiani de Souza Weimann |
| collection | DOAJ |
| description | Abstract Cutaneous metastases from primary internal malignancies represent 0.7-9% of patients with cancer. We report a 65-year-old female patient referred for evaluation of normochromic papules on the trunk and upper limbs that had been present for three months. A skin biopsy revealed diffuse cutaneous infiltration by small round cell tumors. Immunohistochemistry was positive for AE1/AE3, CK7, estrogen receptor and mammaglobin. The final diagnosis was cutaneous metastasis of occult breast cancer, since the solid primary tumor was not identified. The location of the primary tumor can not be determined in 5-10% of cases. In these cases, 27% are identified before the patient’s death, 57% at autopsy, and the remaining 16% can not be located. |
| first_indexed | 2024-12-18T02:46:09Z |
| format | Article |
| id | doaj.art-4dc99ef0cb5f4eb9a7377934453af900 |
| institution | Directory Open Access Journal |
| issn | 0365-0596 |
| language | English |
| last_indexed | 2024-12-18T02:46:09Z |
| publishDate | 2016-10-01 |
| publisher | Sociedade Brasileira de Dermatologia |
| record_format | Article |
| series | Anais Brasileiros de Dermatologia |
| spelling | doaj.art-4dc99ef0cb5f4eb9a7377934453af9002022-12-21T21:23:34ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962016-10-01915 suppl 110510710.1590/abd1806-4841.20164572Cutaneous metastasis as the first manifestation of occult malignant breast neoplasiaEllem Tatiani de Souza WeimannErica Bruder BoteroCinthia MendesMarcel Alex Soares dos SantosRafael Fantelli SteliniCaroline Romanelli T. ZelenikaAbstract Cutaneous metastases from primary internal malignancies represent 0.7-9% of patients with cancer. We report a 65-year-old female patient referred for evaluation of normochromic papules on the trunk and upper limbs that had been present for three months. A skin biopsy revealed diffuse cutaneous infiltration by small round cell tumors. Immunohistochemistry was positive for AE1/AE3, CK7, estrogen receptor and mammaglobin. The final diagnosis was cutaneous metastasis of occult breast cancer, since the solid primary tumor was not identified. The location of the primary tumor can not be determined in 5-10% of cases. In these cases, 27% are identified before the patient’s death, 57% at autopsy, and the remaining 16% can not be located.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016001100105&tlng=enBreast neoplasmsNeoplasm metastasisSkin |
| spellingShingle | Ellem Tatiani de Souza Weimann Erica Bruder Botero Cinthia Mendes Marcel Alex Soares dos Santos Rafael Fantelli Stelini Caroline Romanelli T. Zelenika Cutaneous metastasis as the first manifestation of occult malignant breast neoplasia Anais Brasileiros de Dermatologia Breast neoplasms Neoplasm metastasis Skin |
| title | Cutaneous metastasis as the first manifestation of occult malignant breast neoplasia |
| title_full | Cutaneous metastasis as the first manifestation of occult malignant breast neoplasia |
| title_fullStr | Cutaneous metastasis as the first manifestation of occult malignant breast neoplasia |
| title_full_unstemmed | Cutaneous metastasis as the first manifestation of occult malignant breast neoplasia |
| title_short | Cutaneous metastasis as the first manifestation of occult malignant breast neoplasia |
| title_sort | cutaneous metastasis as the first manifestation of occult malignant breast neoplasia |
| topic | Breast neoplasms Neoplasm metastasis Skin |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016001100105&tlng=en |
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