ChIAMM: A Mixture Model for Statistical Analysis of Long-Range Chromatin Interactions From ChIA-PET Experiments

ChIAMM: A Mixture Model for Statistical Analysis of Long-Range Chromatin Interactions From ChIA-PET Experiments

Chromatin interaction analysis by paired-end tag sequencing (ChIA-PET) is an important experimental method for detecting specific protein-mediated chromatin loops genome-wide at high resolution. Here, we proposed a new statistical approach with a mixture model, chromatin interaction analysis using m...

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Bibliographic Details
Main Authors: Yibeltal Arega, Hao Jiang, Shuangqi Wang, Jingwen Zhang, Xiaohui Niu, Guoliang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Genetics
Subjects:
ChIA-PET
chromatin interactions
genome-wide
mixture model
bayesian framework
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.616160/full

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