Neuroleptic Malignant Syndrome in a Patient with Corticobasal Degeneration

Parkinson’s disease is a principal underlying disease of neuroleptic malignant syndrome (NMS) occurring in parkinsonian disorders, but NMS may occur in patients with progressive supranuclear palsy and multiple system atrophy. We report first patient with corticobasal degeneration (CBD) who developed...

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Bibliographic Details
Main Authors: Myung Jun Lee, Chul Hyoung Lyoo, Myung Sik Lee
Format: Article
Language:English
Published: Korean Movement Disorder Society 2011-10-01
Series:Journal of Movement Disorders
Subjects:
Online Access:http://e-jmd.org/upload/jmd-4-2-73-5.pdf
Description
Summary:Parkinson’s disease is a principal underlying disease of neuroleptic malignant syndrome (NMS) occurring in parkinsonian disorders, but NMS may occur in patients with progressive supranuclear palsy and multiple system atrophy. We report first patient with corticobasal degeneration (CBD) who developed NMS after abrupt reduction of antiparkinsonian medication and concurrent infection. It should be kept in mind that the prevention of infectious illness, which is common complication in parkinson-plus syndrome, is important, and dose reduction or withdrawal of anti-parkinsonian medications should be carefully performed even in the patients with CBD who are expected to be unresponsive to levodopa treatment.
ISSN:2005-940X
2093-4939