Neuroleptic Malignant Syndrome in a Patient with Corticobasal Degeneration

Parkinson’s disease is a principal underlying disease of neuroleptic malignant syndrome (NMS) occurring in parkinsonian disorders, but NMS may occur in patients with progressive supranuclear palsy and multiple system atrophy. We report first patient with corticobasal degeneration (CBD) who developed...

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Main Authors: Myung Jun Lee, Chul Hyoung Lyoo, Myung Sik Lee
Format: Article
Language:English
Published: Korean Movement Disorder Society 2011-10-01
Series:Journal of Movement Disorders
Subjects:
Online Access:http://e-jmd.org/upload/jmd-4-2-73-5.pdf
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author Myung Jun Lee
Chul Hyoung Lyoo
Myung Sik Lee
author_facet Myung Jun Lee
Chul Hyoung Lyoo
Myung Sik Lee
author_sort Myung Jun Lee
collection DOAJ
description Parkinson’s disease is a principal underlying disease of neuroleptic malignant syndrome (NMS) occurring in parkinsonian disorders, but NMS may occur in patients with progressive supranuclear palsy and multiple system atrophy. We report first patient with corticobasal degeneration (CBD) who developed NMS after abrupt reduction of antiparkinsonian medication and concurrent infection. It should be kept in mind that the prevention of infectious illness, which is common complication in parkinson-plus syndrome, is important, and dose reduction or withdrawal of anti-parkinsonian medications should be carefully performed even in the patients with CBD who are expected to be unresponsive to levodopa treatment.
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spelling doaj.art-4dcd268b1e414f249c9df74cd99822f82023-09-02T18:53:32ZengKorean Movement Disorder SocietyJournal of Movement Disorders2005-940X2093-49392011-10-0142737410.14802/jmd.1101527Neuroleptic Malignant Syndrome in a Patient with Corticobasal DegenerationMyung Jun LeeChul Hyoung LyooMyung Sik LeeParkinson’s disease is a principal underlying disease of neuroleptic malignant syndrome (NMS) occurring in parkinsonian disorders, but NMS may occur in patients with progressive supranuclear palsy and multiple system atrophy. We report first patient with corticobasal degeneration (CBD) who developed NMS after abrupt reduction of antiparkinsonian medication and concurrent infection. It should be kept in mind that the prevention of infectious illness, which is common complication in parkinson-plus syndrome, is important, and dose reduction or withdrawal of anti-parkinsonian medications should be carefully performed even in the patients with CBD who are expected to be unresponsive to levodopa treatment.http://e-jmd.org/upload/jmd-4-2-73-5.pdfCorticobasal degenerationNeuroleptic malignant syndrome
spellingShingle Myung Jun Lee
Chul Hyoung Lyoo
Myung Sik Lee
Neuroleptic Malignant Syndrome in a Patient with Corticobasal Degeneration
Journal of Movement Disorders
Corticobasal degeneration
Neuroleptic malignant syndrome
title Neuroleptic Malignant Syndrome in a Patient with Corticobasal Degeneration
title_full Neuroleptic Malignant Syndrome in a Patient with Corticobasal Degeneration
title_fullStr Neuroleptic Malignant Syndrome in a Patient with Corticobasal Degeneration
title_full_unstemmed Neuroleptic Malignant Syndrome in a Patient with Corticobasal Degeneration
title_short Neuroleptic Malignant Syndrome in a Patient with Corticobasal Degeneration
title_sort neuroleptic malignant syndrome in a patient with corticobasal degeneration
topic Corticobasal degeneration
Neuroleptic malignant syndrome
url http://e-jmd.org/upload/jmd-4-2-73-5.pdf
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AT chulhyounglyoo neurolepticmalignantsyndromeinapatientwithcorticobasaldegeneration
AT myungsiklee neurolepticmalignantsyndromeinapatientwithcorticobasaldegeneration