Uterine wall thickness at the second trimester can predict subsequent preterm delivery in pregnancies with adenomyosis
Objectives: We assessed the usefulness of ultrasonography (USG) findings of adenomyosis during pregnancy in the prediction of subsequent preterm delivery. Materials and methods: We included consecutive pregnant women who underwent first trimester ultrasonography in our institution, confirmed as havi...
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| Format: | Article |
| Language: | English |
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Elsevier
2019-09-01
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| Series: | Taiwanese Journal of Obstetrics & Gynecology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1028455919301597 |
| _version_ | 1818096777737273344 |
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| author | Yoo-Min Kim Soo Hyun Kim Ji-Hye Kim Ji-Hee Sung Suk-Joo Choi Soo-young Oh Cheong-Rae Roh |
| author_facet | Yoo-Min Kim Soo Hyun Kim Ji-Hye Kim Ji-Hee Sung Suk-Joo Choi Soo-young Oh Cheong-Rae Roh |
| author_sort | Yoo-Min Kim |
| collection | DOAJ |
| description | Objectives: We assessed the usefulness of ultrasonography (USG) findings of adenomyosis during pregnancy in the prediction of subsequent preterm delivery. Materials and methods: We included consecutive pregnant women who underwent first trimester ultrasonography in our institution, confirmed as having adenomyosis and subsequently delivered in our institution from January 2006 to April 2018. The subjects were classified into two groups: preterm delivery group and term delivery group. Information of maximal uterine wall thickness measured at first trimester and second trimester, maternal characteristics, pregnancy outcomes, and neonatal outcomes were reviewed and compared between preterm and term delivery group. Results: A total of 57 pregnancies were included in this study, and 14 women (24.5%) delivered before 37 weeks of pregnancy. The women from the preterm delivery group had a significantly thicker uterine wall during the second trimester of pregnancy compared to the women from the term delivery group (4.49 ± 1.62 cm vs. 3.05 ± 1.6 cm, p = 0.004). From the first trimester to the second trimester of pregnancy, uterine wall thickness showed a significantly smaller decrease in the preterm delivery group than the term delivery group (−0.42 ± 0.93 cm vs. −1.04 ± 0.89 cm, p = 0.02). By receiver operating characteristics (ROC) curve analysis, uterine wall thickness greater than 4.6 cm in the second trimester of pregnancy showed 57.1% sensitivity, 86.1% specificity, 57.1% positive predictive value (PPV) and 86.1% negative predictive value (NPV) for subsequent preterm delivery (area under curve = 0.758). Conclusions: Uterine wall thickness measurement in second trimester can help to identify preterm delivery in pregnant women with adenomyosis. Keywords: Adenomyosis, Preterm delivery, Ultrasonography |
| first_indexed | 2024-12-10T23:10:01Z |
| format | Article |
| id | doaj.art-4dcd7ee3367c403fa455fa111abc26b5 |
| institution | Directory Open Access Journal |
| issn | 1028-4559 |
| language | English |
| last_indexed | 2024-12-10T23:10:01Z |
| publishDate | 2019-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Taiwanese Journal of Obstetrics & Gynecology |
| spelling | doaj.art-4dcd7ee3367c403fa455fa111abc26b52022-12-22T01:29:57ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592019-09-01585598603Uterine wall thickness at the second trimester can predict subsequent preterm delivery in pregnancies with adenomyosisYoo-Min Kim0Soo Hyun Kim1Ji-Hye Kim2Ji-Hee Sung3Suk-Joo Choi4Soo-young Oh5Cheong-Rae Roh6Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of KoreaDepartment of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of KoreaDepartment of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of KoreaDepartment of Obstetrics & Gynecology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of KoreaDepartment of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of KoreaDepartment of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of KoreaDepartment of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; Corresponding author. 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea. Fax: +82 2 3410 0630.Objectives: We assessed the usefulness of ultrasonography (USG) findings of adenomyosis during pregnancy in the prediction of subsequent preterm delivery. Materials and methods: We included consecutive pregnant women who underwent first trimester ultrasonography in our institution, confirmed as having adenomyosis and subsequently delivered in our institution from January 2006 to April 2018. The subjects were classified into two groups: preterm delivery group and term delivery group. Information of maximal uterine wall thickness measured at first trimester and second trimester, maternal characteristics, pregnancy outcomes, and neonatal outcomes were reviewed and compared between preterm and term delivery group. Results: A total of 57 pregnancies were included in this study, and 14 women (24.5%) delivered before 37 weeks of pregnancy. The women from the preterm delivery group had a significantly thicker uterine wall during the second trimester of pregnancy compared to the women from the term delivery group (4.49 ± 1.62 cm vs. 3.05 ± 1.6 cm, p = 0.004). From the first trimester to the second trimester of pregnancy, uterine wall thickness showed a significantly smaller decrease in the preterm delivery group than the term delivery group (−0.42 ± 0.93 cm vs. −1.04 ± 0.89 cm, p = 0.02). By receiver operating characteristics (ROC) curve analysis, uterine wall thickness greater than 4.6 cm in the second trimester of pregnancy showed 57.1% sensitivity, 86.1% specificity, 57.1% positive predictive value (PPV) and 86.1% negative predictive value (NPV) for subsequent preterm delivery (area under curve = 0.758). Conclusions: Uterine wall thickness measurement in second trimester can help to identify preterm delivery in pregnant women with adenomyosis. Keywords: Adenomyosis, Preterm delivery, Ultrasonographyhttp://www.sciencedirect.com/science/article/pii/S1028455919301597 |
| spellingShingle | Yoo-Min Kim Soo Hyun Kim Ji-Hye Kim Ji-Hee Sung Suk-Joo Choi Soo-young Oh Cheong-Rae Roh Uterine wall thickness at the second trimester can predict subsequent preterm delivery in pregnancies with adenomyosis Taiwanese Journal of Obstetrics & Gynecology |
| title | Uterine wall thickness at the second trimester can predict subsequent preterm delivery in pregnancies with adenomyosis |
| title_full | Uterine wall thickness at the second trimester can predict subsequent preterm delivery in pregnancies with adenomyosis |
| title_fullStr | Uterine wall thickness at the second trimester can predict subsequent preterm delivery in pregnancies with adenomyosis |
| title_full_unstemmed | Uterine wall thickness at the second trimester can predict subsequent preterm delivery in pregnancies with adenomyosis |
| title_short | Uterine wall thickness at the second trimester can predict subsequent preterm delivery in pregnancies with adenomyosis |
| title_sort | uterine wall thickness at the second trimester can predict subsequent preterm delivery in pregnancies with adenomyosis |
| url | http://www.sciencedirect.com/science/article/pii/S1028455919301597 |
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