Retinoic Acid Improves the Recovery of Replication-Competent Virus from Latent SIV Infected Cells

Retinoic Acid Improves the Recovery of Replication-Competent Virus from Latent SIV Infected Cells

The accurate estimation and eradication of Human Immunodeficiency Virus (HIV) viral reservoirs is limited by the incomplete reactivation of cells harboring the latent replication-competent virus. We investigated whether the in vitro and in vivo addition of retinoic acid (RA) enhances virus replicati...

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Bibliographic Details
Main Authors: Omalla A. Olwenyi, Arpan Acharya, Nanda Kishore Routhu, Keely Pierzchalski, Jace W. Jones, Maureen A. Kane, Neil Sidell, Mahesh Mohan, Siddappa N. Byrareddy
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
immune activation
retinoic acid
CD4 T cells
PBMCs
SIV
viral load and provirus
Online Access:https://www.mdpi.com/2073-4409/9/9/2076

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