Peripheral nerve stimulation enables somatosensory feedback while suppressing phantom limb pain in transradial amputees
To simultaneously treat phantom limb pain (PLP) and restore somatic sensations using peripheral nerve stimulation (PNS), two bilateral transradial amputees were implanted with stimulating electrodes in the proximity of the medial, ulnar and radial nerves. Application of PNS evoked tactile and propri...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-05-01
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| Series: | Brain Stimulation |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1935861X23017618 |
| _version_ | 1797798066206539776 |
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| author | Gurgen Soghoyan Artur Biktimirov Yury Matvienko Ilya Chekh Mikhail Sintsov Mikhail A. Lebedev |
| author_facet | Gurgen Soghoyan Artur Biktimirov Yury Matvienko Ilya Chekh Mikhail Sintsov Mikhail A. Lebedev |
| author_sort | Gurgen Soghoyan |
| collection | DOAJ |
| description | To simultaneously treat phantom limb pain (PLP) and restore somatic sensations using peripheral nerve stimulation (PNS), two bilateral transradial amputees were implanted with stimulating electrodes in the proximity of the medial, ulnar and radial nerves. Application of PNS evoked tactile and proprioceptive sensations in the phantom hand. Both patients learned to determine the shape of invisible objects by scanning a computer tablet with a stylus while receiving feedback based on PNS or transcutaneous electrical nerve stimulation (TENS). Оne patient learned to use PNS as feedback from the prosthetic hand that grasped objects of different sizes. PNS abolished PLP completely in one patient and reduced it by 40–70% in the other. We suggest incorporating PNS and/or TENS in active tasks to reduce PLP and restore sensations in amputees. |
| first_indexed | 2024-03-13T03:58:55Z |
| format | Article |
| id | doaj.art-4dcf497139b14af3baaf16fad76ee343 |
| institution | Directory Open Access Journal |
| issn | 1935-861X |
| language | English |
| last_indexed | 2024-03-13T03:58:55Z |
| publishDate | 2023-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brain Stimulation |
| spelling | doaj.art-4dcf497139b14af3baaf16fad76ee3432023-06-22T05:02:42ZengElsevierBrain Stimulation1935-861X2023-05-01163756758Peripheral nerve stimulation enables somatosensory feedback while suppressing phantom limb pain in transradial amputeesGurgen Soghoyan0Artur Biktimirov1Yury Matvienko2Ilya Chekh3Mikhail Sintsov4Mikhail A. Lebedev5Corresponding author.; Vladimir Zelman Center for Neurobiology and Brain Rehabilitation, Skolkovo Institute of Science and Technology, Moscow, RussiaLaboratory of Experimental and Translational Medicine, School of Medicine, Far Eastern Federal University, Vladivostok, Russia; Motorica LLC, Moscow, Russia; Far Eastern Federal University, Medical Center, Department of Neurosurgery, 10 k 25, settlement Ajax, Russky Island, 690922, Vladivostok, RussiaMotorica LLC, Moscow, RussiaMotorica LLC, Moscow, RussiaVladimir Zelman Center for Neurobiology and Brain Rehabilitation, Skolkovo Institute of Science and Technology, Moscow, Russia; Motorica LLC, Moscow, RussiaFaculty of Mechanics and Mathematics, Lomonosov Moscow State University, Moscow, Russia; Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences, Saint-Petersburg, RussiaTo simultaneously treat phantom limb pain (PLP) and restore somatic sensations using peripheral nerve stimulation (PNS), two bilateral transradial amputees were implanted with stimulating electrodes in the proximity of the medial, ulnar and radial nerves. Application of PNS evoked tactile and proprioceptive sensations in the phantom hand. Both patients learned to determine the shape of invisible objects by scanning a computer tablet with a stylus while receiving feedback based on PNS or transcutaneous electrical nerve stimulation (TENS). Оne patient learned to use PNS as feedback from the prosthetic hand that grasped objects of different sizes. PNS abolished PLP completely in one patient and reduced it by 40–70% in the other. We suggest incorporating PNS and/or TENS in active tasks to reduce PLP and restore sensations in amputees.http://www.sciencedirect.com/science/article/pii/S1935861X23017618Peripheral nerve stimulationNeuroprostheticsNeuromodulationPhantom limbPhantom limb painSensory restoration |
| spellingShingle | Gurgen Soghoyan Artur Biktimirov Yury Matvienko Ilya Chekh Mikhail Sintsov Mikhail A. Lebedev Peripheral nerve stimulation enables somatosensory feedback while suppressing phantom limb pain in transradial amputees Brain Stimulation Peripheral nerve stimulation Neuroprosthetics Neuromodulation Phantom limb Phantom limb pain Sensory restoration |
| title | Peripheral nerve stimulation enables somatosensory feedback while suppressing phantom limb pain in transradial amputees |
| title_full | Peripheral nerve stimulation enables somatosensory feedback while suppressing phantom limb pain in transradial amputees |
| title_fullStr | Peripheral nerve stimulation enables somatosensory feedback while suppressing phantom limb pain in transradial amputees |
| title_full_unstemmed | Peripheral nerve stimulation enables somatosensory feedback while suppressing phantom limb pain in transradial amputees |
| title_short | Peripheral nerve stimulation enables somatosensory feedback while suppressing phantom limb pain in transradial amputees |
| title_sort | peripheral nerve stimulation enables somatosensory feedback while suppressing phantom limb pain in transradial amputees |
| topic | Peripheral nerve stimulation Neuroprosthetics Neuromodulation Phantom limb Phantom limb pain Sensory restoration |
| url | http://www.sciencedirect.com/science/article/pii/S1935861X23017618 |
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