Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009

Abstract A detailed chemical investigation of the secondary metabolites produced by the endophytic fungus Xylaria sp. isolated from the stems of Isodon sculponeatus afforded six new compounds, xylariahgins A–F (1–6), two new natural products (7 and 8), along with two known compounds (9 and 10) (Fig....

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Main Authors: Rong Chen, Jian-Wei Tang, Xing-Ren Li, Miao Liu, Wen-Ping Ding, Yuan-Fei Zhou, Wei-Guang Wang, Xue Du, Han-Dong Sun, Pema-Tenzin Puno
Format: Article
Language:English
Published: SpringerOpen 2018-03-01
Series:Natural Products and Bioprospecting
Subjects:
Online Access:http://link.springer.com/article/10.1007/s13659-018-0158-x
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author Rong Chen
Jian-Wei Tang
Xing-Ren Li
Miao Liu
Wen-Ping Ding
Yuan-Fei Zhou
Wei-Guang Wang
Xue Du
Han-Dong Sun
Pema-Tenzin Puno
author_facet Rong Chen
Jian-Wei Tang
Xing-Ren Li
Miao Liu
Wen-Ping Ding
Yuan-Fei Zhou
Wei-Guang Wang
Xue Du
Han-Dong Sun
Pema-Tenzin Puno
author_sort Rong Chen
collection DOAJ
description Abstract A detailed chemical investigation of the secondary metabolites produced by the endophytic fungus Xylaria sp. isolated from the stems of Isodon sculponeatus afforded six new compounds, xylariahgins A–F (1–6), two new natural products (7 and 8), along with two known compounds (9 and 10) (Fig. 1). The structures of all compounds were unambiguously established by analyzing their spectroscopic data or referring to pertinent literature. Compounds 1–8 were tested for their cytotoxic activity against five human tumor cell lines.
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spelling doaj.art-4dd13ef718e04f30896cebd85bc617d72022-12-22T02:01:23ZengSpringerOpenNatural Products and Bioprospecting2192-21952192-22092018-03-018212112910.1007/s13659-018-0158-xSecondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009Rong Chen0Jian-Wei Tang1Xing-Ren Li2Miao Liu3Wen-Ping Ding4Yuan-Fei Zhou5Wei-Guang Wang6Xue Du7Han-Dong Sun8Pema-Tenzin Puno9School of Chemical Science and Technology, Yunnan UniversityState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesSchool of Chemical Science and Technology, Yunnan UniversityState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesAbstract A detailed chemical investigation of the secondary metabolites produced by the endophytic fungus Xylaria sp. isolated from the stems of Isodon sculponeatus afforded six new compounds, xylariahgins A–F (1–6), two new natural products (7 and 8), along with two known compounds (9 and 10) (Fig. 1). The structures of all compounds were unambiguously established by analyzing their spectroscopic data or referring to pertinent literature. Compounds 1–8 were tested for their cytotoxic activity against five human tumor cell lines.http://link.springer.com/article/10.1007/s13659-018-0158-xEndophytic fungusXylaria sp.Secondary metabolitesCytotoxicity
spellingShingle Rong Chen
Jian-Wei Tang
Xing-Ren Li
Miao Liu
Wen-Ping Ding
Yuan-Fei Zhou
Wei-Guang Wang
Xue Du
Han-Dong Sun
Pema-Tenzin Puno
Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009
Natural Products and Bioprospecting
Endophytic fungus
Xylaria sp.
Secondary metabolites
Cytotoxicity
title Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009
title_full Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009
title_fullStr Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009
title_full_unstemmed Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009
title_short Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009
title_sort secondary metabolites from the endophytic fungus xylaria sp hg1009
topic Endophytic fungus
Xylaria sp.
Secondary metabolites
Cytotoxicity
url http://link.springer.com/article/10.1007/s13659-018-0158-x
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