A Combination Of Amoxicillian And Clavulanic Acid In The Treatment Of Impetigo In Children
Amoxicillin plus clavulanic acid (ACA) a combination of potentially effective antibiotic against beta-lactamase producing bacteria was compared with that of amoxicillin, erythomycin and co-trimoxazole in an open label, randomized trial in 100 children with mild to severe impetigo. 22% chi...
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
1998-01-01
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| Series: | Indian Journal of Dermatology |
| Online Access: | http://www.e-ijd.org/article.asp?issn=0019-5154;year=1998;volume=43;issue=1;spage=7;epage=9;aulast=P;type=0 |
| _version_ | 1819030796347899904 |
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| author | P K Kar Col |
| author_facet | P K Kar Col |
| author_sort | P K Kar Col |
| collection | DOAJ |
| description | Amoxicillin plus clavulanic acid (ACA) a combination of potentially effective antibiotic against beta-lactamase producing bacteria was compared with that of amoxicillin, erythomycin and co-trimoxazole in an open label, randomized trial in 100 children with mild to severe impetigo. 22% children had mild, 25% had moderate and 53% children had severe impetigo. Pure growth of S. aureus was isolated in 68% children, S.pyogenes in 26% and both staphyto and streptococci in 6% children. In mild to moderate infection 100% children receiving ACA were cured clinically after first week, whereas 7 out of 15(46.6%) children in amoxicillin group, 7 out of 13(53.1%) children in erythromycin group and 4 out 12 (33.3%) children in co-trimoxazole group showed clinical cure after first week. In severe impetigo 46.1% children receiving ACA, 20% children in amoxicillin group, 16.6% children inerythromycin group and 7.6% in co-trimoxazole group showed clinical cure on therapy after one week. ACA was well tolerated in children. |
| first_indexed | 2024-12-21T06:35:51Z |
| format | Article |
| id | doaj.art-4dd5cc5aa07143cb954bee7b2601b002 |
| institution | Directory Open Access Journal |
| issn | 0019-5154 1998-3611 |
| language | English |
| last_indexed | 2024-12-21T06:35:51Z |
| publishDate | 1998-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Dermatology |
| spelling | doaj.art-4dd5cc5aa07143cb954bee7b2601b0022022-12-21T19:12:52ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36111998-01-0143179A Combination Of Amoxicillian And Clavulanic Acid In The Treatment Of Impetigo In ChildrenP K Kar ColAmoxicillin plus clavulanic acid (ACA) a combination of potentially effective antibiotic against beta-lactamase producing bacteria was compared with that of amoxicillin, erythomycin and co-trimoxazole in an open label, randomized trial in 100 children with mild to severe impetigo. 22% children had mild, 25% had moderate and 53% children had severe impetigo. Pure growth of S. aureus was isolated in 68% children, S.pyogenes in 26% and both staphyto and streptococci in 6% children. In mild to moderate infection 100% children receiving ACA were cured clinically after first week, whereas 7 out of 15(46.6%) children in amoxicillin group, 7 out of 13(53.1%) children in erythromycin group and 4 out 12 (33.3%) children in co-trimoxazole group showed clinical cure after first week. In severe impetigo 46.1% children receiving ACA, 20% children in amoxicillin group, 16.6% children inerythromycin group and 7.6% in co-trimoxazole group showed clinical cure on therapy after one week. ACA was well tolerated in children.http://www.e-ijd.org/article.asp?issn=0019-5154;year=1998;volume=43;issue=1;spage=7;epage=9;aulast=P;type=0 |
| spellingShingle | P K Kar Col A Combination Of Amoxicillian And Clavulanic Acid In The Treatment Of Impetigo In Children Indian Journal of Dermatology |
| title | A Combination Of Amoxicillian And Clavulanic Acid In The Treatment Of Impetigo In Children |
| title_full | A Combination Of Amoxicillian And Clavulanic Acid In The Treatment Of Impetigo In Children |
| title_fullStr | A Combination Of Amoxicillian And Clavulanic Acid In The Treatment Of Impetigo In Children |
| title_full_unstemmed | A Combination Of Amoxicillian And Clavulanic Acid In The Treatment Of Impetigo In Children |
| title_short | A Combination Of Amoxicillian And Clavulanic Acid In The Treatment Of Impetigo In Children |
| title_sort | combination of amoxicillian and clavulanic acid in the treatment of impetigo in children |
| url | http://www.e-ijd.org/article.asp?issn=0019-5154;year=1998;volume=43;issue=1;spage=7;epage=9;aulast=P;type=0 |
| work_keys_str_mv | AT pkkarcol acombinationofamoxicillianandclavulanicacidinthetreatmentofimpetigoinchildren AT pkkarcol combinationofamoxicillianandclavulanicacidinthetreatmentofimpetigoinchildren |