Temporal trends in colorectal cancer mortality rates (1999–2022) in the United States
Abstract Colorectal cancer (CRC) ranks as the third leading cause of cancer‐related deaths in the United States (U.S.). Our study aims to analyze CRC mortality patterns in the U.S., focusing on gender and age groups from 1999 to 2022. We analyzed Age‐Adjusted Mortality Rates (AAMRs) for CRC‐related...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-03-01
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| Series: | Cancer Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/cnr2.2012 |
| _version_ | 1827303920350789632 |
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| author | Fariha Ilyas Eiman Ahmed Hassam Ali Maheen Ilyas Shiza Sarfraz Mahnoor Khalid Muhammad Khalaf Prashant Reddy Mudireddy |
| author_facet | Fariha Ilyas Eiman Ahmed Hassam Ali Maheen Ilyas Shiza Sarfraz Mahnoor Khalid Muhammad Khalaf Prashant Reddy Mudireddy |
| author_sort | Fariha Ilyas |
| collection | DOAJ |
| description | Abstract Colorectal cancer (CRC) ranks as the third leading cause of cancer‐related deaths in the United States (U.S.). Our study aims to analyze CRC mortality patterns in the U.S., focusing on gender and age groups from 1999 to 2022. We analyzed Age‐Adjusted Mortality Rates (AAMRs) for CRC‐related deaths using the CDC Wide‐ranging Online Data for Epidemiologic Research (CDC WONDER) database and assessed differences between age and sex. CRC‐related mortality decreased significantly from 1999 to 2011 (−2.81% APC) and from 2011 to 2020 (−1.95% APC) but a not significant uptrend from 2020 to 2022 (2% APC). Males experienced a more significant decrease. Among age groups, crude mortality decreased until 2020, except in age group 45–54, which showed an annual increase in mortality of 0.9% from 2004 to 2022. Furthermore, individuals aged 75–84 and 85+ saw a nonsignificant annual increase of 1.8% and 4.5% from 2020 to 2022, respectively. Our study highlights a significant decline in age and gender‐specific CRC‐related mortality from 1999 to 2020. However, the worrisome uptrend observed in the younger age group of 45–54 emphasizes the importance of implementing targeted public health measures and evidence‐based interventions. |
| first_indexed | 2024-04-24T17:10:26Z |
| format | Article |
| id | doaj.art-4dd7a11f12474d1c985f289a6f35c08e |
| institution | Directory Open Access Journal |
| issn | 2573-8348 |
| language | English |
| last_indexed | 2024-04-24T17:10:26Z |
| publishDate | 2024-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Reports |
| spelling | doaj.art-4dd7a11f12474d1c985f289a6f35c08e2024-03-28T12:30:35ZengWileyCancer Reports2573-83482024-03-0173n/an/a10.1002/cnr2.2012Temporal trends in colorectal cancer mortality rates (1999–2022) in the United StatesFariha Ilyas0Eiman Ahmed1Hassam Ali2Maheen Ilyas3Shiza Sarfraz4Mahnoor Khalid5Muhammad Khalaf6Prashant Reddy Mudireddy7Department of Internal Medicine ECU Health Medical Center Greenville North Carolina USADepartment of Library and Information Science Rutgers University New Brunswick New Jersey USADepartment of Gastroenterology ECU Health Medical Center Greenville North Carolina USAOsteopathic Medical Student III, New York Institute of Technology College of Osteopathic Medicine Old Westbury New York USADepartment of Internal Medicine Quaid‐e‐Azam Medical College Bahawalpur Punjab PakistanDepartment of Internal Medicine Foundation University Medical College Rawalpindi PakistanDepartment of Gastroenterology ECU Health Medical Center Greenville North Carolina USADepartment of Gastroenterology ECU Health Medical Center Greenville North Carolina USAAbstract Colorectal cancer (CRC) ranks as the third leading cause of cancer‐related deaths in the United States (U.S.). Our study aims to analyze CRC mortality patterns in the U.S., focusing on gender and age groups from 1999 to 2022. We analyzed Age‐Adjusted Mortality Rates (AAMRs) for CRC‐related deaths using the CDC Wide‐ranging Online Data for Epidemiologic Research (CDC WONDER) database and assessed differences between age and sex. CRC‐related mortality decreased significantly from 1999 to 2011 (−2.81% APC) and from 2011 to 2020 (−1.95% APC) but a not significant uptrend from 2020 to 2022 (2% APC). Males experienced a more significant decrease. Among age groups, crude mortality decreased until 2020, except in age group 45–54, which showed an annual increase in mortality of 0.9% from 2004 to 2022. Furthermore, individuals aged 75–84 and 85+ saw a nonsignificant annual increase of 1.8% and 4.5% from 2020 to 2022, respectively. Our study highlights a significant decline in age and gender‐specific CRC‐related mortality from 1999 to 2020. However, the worrisome uptrend observed in the younger age group of 45–54 emphasizes the importance of implementing targeted public health measures and evidence‐based interventions.https://doi.org/10.1002/cnr2.2012colorectal neoplasmsdisease progressionepidemiologymortalitypopulation surveillance |
| spellingShingle | Fariha Ilyas Eiman Ahmed Hassam Ali Maheen Ilyas Shiza Sarfraz Mahnoor Khalid Muhammad Khalaf Prashant Reddy Mudireddy Temporal trends in colorectal cancer mortality rates (1999–2022) in the United States Cancer Reports colorectal neoplasms disease progression epidemiology mortality population surveillance |
| title | Temporal trends in colorectal cancer mortality rates (1999–2022) in the United States |
| title_full | Temporal trends in colorectal cancer mortality rates (1999–2022) in the United States |
| title_fullStr | Temporal trends in colorectal cancer mortality rates (1999–2022) in the United States |
| title_full_unstemmed | Temporal trends in colorectal cancer mortality rates (1999–2022) in the United States |
| title_short | Temporal trends in colorectal cancer mortality rates (1999–2022) in the United States |
| title_sort | temporal trends in colorectal cancer mortality rates 1999 2022 in the united states |
| topic | colorectal neoplasms disease progression epidemiology mortality population surveillance |
| url | https://doi.org/10.1002/cnr2.2012 |
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