Emerging Role of USP8, HMGA, and Non-Coding RNAs in Pituitary Tumorigenesis
Two novel molecular mechanisms with a driver role in pituitary tumorigenesis have been recently identified. They are (a) mutations in the Ubiquitin-Specific Protease 8 (USP8) gene in corticotroph tumors and (b) overexpression of the <i>HMGA1</i> and <i>HMGA2</i> genes in most...
Main Authors: | Daniela D’Angelo, Marco De Martino, Claudio Arra, Alfredo Fusco |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-09-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/11/9/1302 |
Similar Items
-
Hmga1/Hmga2 double knock-out mice display a “superpygmy” phenotype
by: Antonella Federico, et al.
Published: (2014-04-01) -
HMGA1-Regulating microRNAs Let-7a and miR-26a are Downregulated in Human Seminomas
by: Marco De Martino, et al.
Published: (2020-04-01) -
HMGA2 Antisense Long Non-coding RNAs as New Players in the Regulation of HMGA2 Expression and Pancreatic Cancer Promotion
by: Gloria Ros, et al.
Published: (2020-01-01) -
SST5 expression and USP8 mutation in functioning and silent corticotroph pituitary tumors
by: Solène Castellnou, et al.
Published: (2020-03-01) -
Genetic Profiling of a Cohort of Italian Patients with ACTH-Secreting Pituitary Tumors and Characterization of a Novel <i>USP8</i> Gene Variant
by: Donatella Treppiedi, et al.
Published: (2021-08-01)