The impact of finasteride and dutasteride treatments on proliferation, apoptosis, androgen receptor, 5α-reductase 1 and 5α-reductase 2 in TRAMP mouse prostates

The impact of finasteride and dutasteride treatments on proliferation, apoptosis, androgen receptor, 5α-reductase 1 and 5α-reductase 2 in TRAMP mouse prostates

Background: Previously, we studied the effect of finasteride- or dutasteride-containing diets in male C57BL/6 TRAMP x FVB mice. Pre (6 weeks of age) and post (12 weeks of age) groups received finasteride or dutasteride to determine the efficacy of these pharmaceuticals on prostate cancer (PCa) devel...

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Bibliographic Details
Main Authors: Alexander B. Opoku-Acheampong, Jamie N. Henningson, Brian L. Lindshield
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Heliyon
Subjects:
Pathology
Cell biology
Physiology
Oncology
Cancer research
Anatomy
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844016325063

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