Impact of green tea extract on serum lipid of postmenopausal women: A randomized controlled trial
Background: This study aimed to evaluate the impact of green tea extract on serum lipid level in postmenopausal women. Method: In this randomized controlled trial 100 postmenopausal women with an abnormality in at least one lipid profile were recruited and randomly assigned to one of the two groups:...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2018-07-01
|
| Series: | Journal of Traditional and Complementary Medicine |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2225411017300925 |
| _version_ | 1828232418344042496 |
|---|---|
| author | Mitra Tadayon Somaneh Movahedi Parvin Abedi Amir Syahpoosh |
| author_facet | Mitra Tadayon Somaneh Movahedi Parvin Abedi Amir Syahpoosh |
| author_sort | Mitra Tadayon |
| collection | DOAJ |
| description | Background: This study aimed to evaluate the impact of green tea extract on serum lipid level in postmenopausal women. Method: In this randomized controlled trial 100 postmenopausal women with an abnormality in at least one lipid profile were recruited and randomly assigned to one of the two groups: green tea extract (n = 50) and control group (n = 50). The intervention group received two capsules (400 mg) of green tea extract two times daily; the control group received a placebo for 4 weeks. The serum level of the lipid profile (total cholesterol, low density lipoprotein (LDL), high density lipoprotein (HDL), triglyceride, and fasting blood sugar) was measured at baseline and 4 weeks after intervention. Results: In total, 79 women completed the study. The mean total cholesterol in the green tea group was significantly decreased after 4 weeks of intervention (mean difference −18.1 vs. −5 mg/dL in the green tea and placebo groups, p < 0.04). The triglyceride and LDL also decreased significantly in the green tea group compared to the control group (p = 0.002 and p = 0.04 respectively). The level of HDL and fasting blood sugar did not change within the group and between groups. Conclusion: Green tea extract is cost-effective way to decrease lipid profile in postmenopausal women without major side effects. Using this herb is recommended in women who have slight lipid profile abnormalities. Keywords: Low density lipoprotein, Triglyceride, High density lipoprotein, Total cholesterol, Green tea extract |
| first_indexed | 2024-04-12T19:21:31Z |
| format | Article |
| id | doaj.art-4de9fcf3b457414281ae06a4ede00d47 |
| institution | Directory Open Access Journal |
| issn | 2225-4110 |
| language | English |
| last_indexed | 2024-04-12T19:21:31Z |
| publishDate | 2018-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Traditional and Complementary Medicine |
| spelling | doaj.art-4de9fcf3b457414281ae06a4ede00d472022-12-22T03:19:34ZengElsevierJournal of Traditional and Complementary Medicine2225-41102018-07-0183391395Impact of green tea extract on serum lipid of postmenopausal women: A randomized controlled trialMitra Tadayon0Somaneh Movahedi1Parvin Abedi2Amir Syahpoosh3Midwifery Department, Menopause & Andropasue Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranMidwifery Department, Menopause & Andropasue Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranMidwifery Department, Menopause & Andropasue Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Corresponding author. 1st Eastern Maroon, No:46, 13th East Kianpars Ave, Ahvaz, 6155975743, Iran.Medical Plant and Natural Products Research Center, Department of Pharmacology, Pharmacy School, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranBackground: This study aimed to evaluate the impact of green tea extract on serum lipid level in postmenopausal women. Method: In this randomized controlled trial 100 postmenopausal women with an abnormality in at least one lipid profile were recruited and randomly assigned to one of the two groups: green tea extract (n = 50) and control group (n = 50). The intervention group received two capsules (400 mg) of green tea extract two times daily; the control group received a placebo for 4 weeks. The serum level of the lipid profile (total cholesterol, low density lipoprotein (LDL), high density lipoprotein (HDL), triglyceride, and fasting blood sugar) was measured at baseline and 4 weeks after intervention. Results: In total, 79 women completed the study. The mean total cholesterol in the green tea group was significantly decreased after 4 weeks of intervention (mean difference −18.1 vs. −5 mg/dL in the green tea and placebo groups, p < 0.04). The triglyceride and LDL also decreased significantly in the green tea group compared to the control group (p = 0.002 and p = 0.04 respectively). The level of HDL and fasting blood sugar did not change within the group and between groups. Conclusion: Green tea extract is cost-effective way to decrease lipid profile in postmenopausal women without major side effects. Using this herb is recommended in women who have slight lipid profile abnormalities. Keywords: Low density lipoprotein, Triglyceride, High density lipoprotein, Total cholesterol, Green tea extracthttp://www.sciencedirect.com/science/article/pii/S2225411017300925 |
| spellingShingle | Mitra Tadayon Somaneh Movahedi Parvin Abedi Amir Syahpoosh Impact of green tea extract on serum lipid of postmenopausal women: A randomized controlled trial Journal of Traditional and Complementary Medicine |
| title | Impact of green tea extract on serum lipid of postmenopausal women: A randomized controlled trial |
| title_full | Impact of green tea extract on serum lipid of postmenopausal women: A randomized controlled trial |
| title_fullStr | Impact of green tea extract on serum lipid of postmenopausal women: A randomized controlled trial |
| title_full_unstemmed | Impact of green tea extract on serum lipid of postmenopausal women: A randomized controlled trial |
| title_short | Impact of green tea extract on serum lipid of postmenopausal women: A randomized controlled trial |
| title_sort | impact of green tea extract on serum lipid of postmenopausal women a randomized controlled trial |
| url | http://www.sciencedirect.com/science/article/pii/S2225411017300925 |
| work_keys_str_mv | AT mitratadayon impactofgreenteaextractonserumlipidofpostmenopausalwomenarandomizedcontrolledtrial AT somanehmovahedi impactofgreenteaextractonserumlipidofpostmenopausalwomenarandomizedcontrolledtrial AT parvinabedi impactofgreenteaextractonserumlipidofpostmenopausalwomenarandomizedcontrolledtrial AT amirsyahpoosh impactofgreenteaextractonserumlipidofpostmenopausalwomenarandomizedcontrolledtrial |