Design and Synthesis of Novel Tetrapeptide Analogues as New Cytotoxic Agents

Design and Synthesis of Novel Tetrapeptide Analogues as New Cytotoxic Agents

New series of compounds based on a tetrapeptide scaffold containing methyl sulfonyl group at the para position of a phenyl ring were synthesized and their cytotoxic activities were examined against several human cancer cell lines including MCF-7 (breast cancer Cell Line), HepG2 (human liver cancer C...

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Bibliographic Details
Main Authors: Mohammad Ali Ahmaditaba, Mohammad Hassan Houshdar Tehrani, Afshin Zarghi, Sorayya Shahosseini, Sara Hariri
Format: Article
Language:English
Published: Shahid Beheshti University of Medical Sciences 2017-09-01
Series:Trends in Peptide and Protein Sciences
Subjects:
cytotoxic activity
methyl sulfonyl group
mtt
synthesis
tetrapeptide scaffold
Online Access:https://journals.sbmu.ac.ir/protein/article/view/17476

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