Prevalence of Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis in patients with bronchial asthma at a tertiary care center in North India

Background: The prevalence of Aspergillus hypersensitivity (AH) and allergic bronchopulmonary aspergillosis (ABPA) has been variably reported. Systematic data regarding Aspergillus sensitization and ABPA are lacking from this part of the country. Objectives: The aim of this study was to evaluate the...

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Main Authors: Alok Nath, Ajmal Khan, Zia Hashim, Jeetendra Kumar Patra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Lung India
Subjects:
Online Access:http://www.lungindia.com/article.asp?issn=0970-2113;year=2017;volume=34;issue=2;spage=150;epage=154;aulast=Nath
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author Alok Nath
Ajmal Khan
Zia Hashim
Jeetendra Kumar Patra
author_facet Alok Nath
Ajmal Khan
Zia Hashim
Jeetendra Kumar Patra
author_sort Alok Nath
collection DOAJ
description Background: The prevalence of Aspergillus hypersensitivity (AH) and allergic bronchopulmonary aspergillosis (ABPA) has been variably reported. Systematic data regarding Aspergillus sensitization and ABPA are lacking from this part of the country. Objectives: The aim of this study was to evaluate the prevalence of AH and ABPA in Uttar Pradesh. Setting and Design: This was prospective observational study. All patients attending outpatient Department of Pulmonary Medicine of our institute were included in the study. Subjects and Methods: Consecutive asthmatic patients underwent screening for ABPA using Aspergillus skin test (AST). Those showing a positive response to AST were further evaluated for ABPA. Results: During the study, 350 patients (192 males, 158 females, mean ± standard deviation age: 38.3 ± 12.8) were screened with AST. One hundred and twenty-three patients (35.1%) were tested positive for AST and 21.7% of patients were diagnosed as ABPA. Conclusions: A high prevalence rate of ABPA was observed at our chest clinic. Although comparable with published data from other tertiary centers, it does not represent the true prevalence rates in asthmatics because of high chances of referral bias.
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spelling doaj.art-4df47feb1ff24adcb6d5d11e7db1817b2022-12-21T17:45:01ZengWolters Kluwer Medknow PublicationsLung India0970-21130974-598X2017-01-0134215015410.4103/0970-2113.201300Prevalence of Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis in patients with bronchial asthma at a tertiary care center in North IndiaAlok NathAjmal KhanZia HashimJeetendra Kumar PatraBackground: The prevalence of Aspergillus hypersensitivity (AH) and allergic bronchopulmonary aspergillosis (ABPA) has been variably reported. Systematic data regarding Aspergillus sensitization and ABPA are lacking from this part of the country. Objectives: The aim of this study was to evaluate the prevalence of AH and ABPA in Uttar Pradesh. Setting and Design: This was prospective observational study. All patients attending outpatient Department of Pulmonary Medicine of our institute were included in the study. Subjects and Methods: Consecutive asthmatic patients underwent screening for ABPA using Aspergillus skin test (AST). Those showing a positive response to AST were further evaluated for ABPA. Results: During the study, 350 patients (192 males, 158 females, mean ± standard deviation age: 38.3 ± 12.8) were screened with AST. One hundred and twenty-three patients (35.1%) were tested positive for AST and 21.7% of patients were diagnosed as ABPA. Conclusions: A high prevalence rate of ABPA was observed at our chest clinic. Although comparable with published data from other tertiary centers, it does not represent the true prevalence rates in asthmatics because of high chances of referral bias.http://www.lungindia.com/article.asp?issn=0970-2113;year=2017;volume=34;issue=2;spage=150;epage=154;aulast=NathAllergic bronchopulmonary aspergillosisAspergillus hypersensitivitybronchial asthma
spellingShingle Alok Nath
Ajmal Khan
Zia Hashim
Jeetendra Kumar Patra
Prevalence of Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis in patients with bronchial asthma at a tertiary care center in North India
Lung India
Allergic bronchopulmonary aspergillosis
Aspergillus hypersensitivity
bronchial asthma
title Prevalence of Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis in patients with bronchial asthma at a tertiary care center in North India
title_full Prevalence of Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis in patients with bronchial asthma at a tertiary care center in North India
title_fullStr Prevalence of Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis in patients with bronchial asthma at a tertiary care center in North India
title_full_unstemmed Prevalence of Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis in patients with bronchial asthma at a tertiary care center in North India
title_short Prevalence of Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis in patients with bronchial asthma at a tertiary care center in North India
title_sort prevalence of aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis in patients with bronchial asthma at a tertiary care center in north india
topic Allergic bronchopulmonary aspergillosis
Aspergillus hypersensitivity
bronchial asthma
url http://www.lungindia.com/article.asp?issn=0970-2113;year=2017;volume=34;issue=2;spage=150;epage=154;aulast=Nath
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