Subcellular Localization of Beta Catenin in Colorectal Non Neoplastic and Neoplastic Lesions

Subcellular Localization of Beta Catenin in Colorectal Non Neoplastic and Neoplastic Lesions

Loss of adenomatous polyposis coli (APC) function is typically an early event in sporadic colorectal cancer (CRC) pathogenesis. The key tumor suppressor function of the APC protein lies in its ability to destabilize free cytoplasmic beta catenin. This lead to the accumulation of nuclear beta caten...

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Bibliographic Details
Main Authors: Diah Rini Handjari, Pamela Abineno, Budiningsih Siregar
Format: Article
Language:English
Published: Universitas Indonesia 2012-01-01
Series:Makara Journal of Health Research
Subjects:
beta catenin
colorectal cancer
colorectal adenoma
chronic colitis
Online Access:http://journal.ui.ac.id/index.php/health/article/view/942

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