The Pharmacokinetics in Mice and Cell Uptake of Thymus Immunosuppressive Pentapeptide Using LC-MS/MS Analysis

The Pharmacokinetics in Mice and Cell Uptake of Thymus Immunosuppressive Pentapeptide Using LC-MS/MS Analysis

Thymus immunosuppressive pentapeptide (TIPP) is a novel anti-inflammatory peptide with high efficacy and low toxicity. This study aims to establish a selective LC-MS/MS method for analyzing the analyte TIPP in biological samples, laying the foundation for further PK and PD studies of TIPP. Protein p...

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Bibliographic Details
Main Authors: Shang Chen, Chenyan Ren, Yuan Ji, Dongke Liu, Xinke Zhang, Fengshan Wang
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Molecules
Subjects:
LC-MS/MS
bioanalytical method development
allergic asthma
pharmacokinetics
cell uptake
Online Access:https://www.mdpi.com/1420-3049/27/13/4256

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