Derivation and Validation of Genome‐Wide Polygenic Score for Ischemic Heart Failure

Derivation and Validation of Genome‐Wide Polygenic Score for Ischemic Heart Failure

Background Despite advances in cardiovascular disease and risk factor management, mortality from ischemic heart failure (HF) in patients with coronary artery disease (CAD) remains high. Given the partial role of genetics in HF and lack of reliable risk stratification tools, we developed and validate...

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Bibliographic Details
Main Authors: Ishan Paranjpe, Noah L. Tsao, Jessica K. De Freitas, Renae Judy, Kumardeep Chaudhary, Iain S. Forrest, Suraj K. Jaladanki, Manish Paranjpe, Pranav Sharma, Benjamin S. Glicksberg, Jagat Narula, Ron Do, Scott M. Damrauer, Girish N. Nadkarni
Format: Article
Language:English
Published: Wiley 2021-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
genomics
heart failure
personalized medicine
polygenic risk score
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.121.021916

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