Incidental Finding of a PSMA-Positive Pancreatic Cancer in a Patient Suffering from a Metastasized PSMA-Positive Prostate Cancer

An 82-year-old man suffering from prostate cancer that was scheduled for a radioreceptor-ligand therapy (RLT) presented with jaundice to our service. An abdominal ultrasound (US) revealed obstructive extrahepatic cholestasis due to a solid lesion located in the uncinate process of the pancreas. The...

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Main Authors: Simon Sirtl, Andrei Todica, Harun Ilhan, Michal Zorniak, Peter Bartenstein, Julia Mayerle
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/11/1/129
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author Simon Sirtl
Andrei Todica
Harun Ilhan
Michal Zorniak
Peter Bartenstein
Julia Mayerle
author_facet Simon Sirtl
Andrei Todica
Harun Ilhan
Michal Zorniak
Peter Bartenstein
Julia Mayerle
author_sort Simon Sirtl
collection DOAJ
description An 82-year-old man suffering from prostate cancer that was scheduled for a radioreceptor-ligand therapy (RLT) presented with jaundice to our service. An abdominal ultrasound (US) revealed obstructive extrahepatic cholestasis due to a solid lesion located in the uncinate process of the pancreas. The Prostate Specific Membrane Antigen (PSMA) PET/CT prior to RLT showed multilocular PSMA positive tumor lesions in the lymph nodes, the lung and the pancreas. On request of the cancer board, an Endoscopic Ultrasound (EUS)-guided Fine-Needle Aspiration (FNA) of the pancreatic mass was performed revealing invasive pancreatic ductal adenocarcinoma incompatible with a prostate cancer metastasis leading to the diagnosis of a PSMA positive pancreatic ductal adenocarcinoma.
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spelling doaj.art-4dfa279bcd43404389eb6058809ceb532023-12-03T13:20:45ZengMDPI AGDiagnostics2075-44182021-01-0111112910.3390/diagnostics11010129Incidental Finding of a PSMA-Positive Pancreatic Cancer in a Patient Suffering from a Metastasized PSMA-Positive Prostate CancerSimon Sirtl0Andrei Todica1Harun Ilhan2Michal Zorniak3Peter Bartenstein4Julia Mayerle5Department of Medicine II, University Hospital, 81377 LMU Munich, GermanyDepartment of Nuclear Medicine, University Hospital, 81377 LMU Munich, GermanyDepartment of Nuclear Medicine, University Hospital, 81377 LMU Munich, GermanyDepartment of Medicine II, University Hospital, 81377 LMU Munich, GermanyDepartment of Nuclear Medicine, University Hospital, 81377 LMU Munich, GermanyDepartment of Medicine II, University Hospital, 81377 LMU Munich, GermanyAn 82-year-old man suffering from prostate cancer that was scheduled for a radioreceptor-ligand therapy (RLT) presented with jaundice to our service. An abdominal ultrasound (US) revealed obstructive extrahepatic cholestasis due to a solid lesion located in the uncinate process of the pancreas. The Prostate Specific Membrane Antigen (PSMA) PET/CT prior to RLT showed multilocular PSMA positive tumor lesions in the lymph nodes, the lung and the pancreas. On request of the cancer board, an Endoscopic Ultrasound (EUS)-guided Fine-Needle Aspiration (FNA) of the pancreatic mass was performed revealing invasive pancreatic ductal adenocarcinoma incompatible with a prostate cancer metastasis leading to the diagnosis of a PSMA positive pancreatic ductal adenocarcinoma.https://www.mdpi.com/2075-4418/11/1/129PSMApancreatic cancerPET
spellingShingle Simon Sirtl
Andrei Todica
Harun Ilhan
Michal Zorniak
Peter Bartenstein
Julia Mayerle
Incidental Finding of a PSMA-Positive Pancreatic Cancer in a Patient Suffering from a Metastasized PSMA-Positive Prostate Cancer
Diagnostics
PSMA
pancreatic cancer
PET
title Incidental Finding of a PSMA-Positive Pancreatic Cancer in a Patient Suffering from a Metastasized PSMA-Positive Prostate Cancer
title_full Incidental Finding of a PSMA-Positive Pancreatic Cancer in a Patient Suffering from a Metastasized PSMA-Positive Prostate Cancer
title_fullStr Incidental Finding of a PSMA-Positive Pancreatic Cancer in a Patient Suffering from a Metastasized PSMA-Positive Prostate Cancer
title_full_unstemmed Incidental Finding of a PSMA-Positive Pancreatic Cancer in a Patient Suffering from a Metastasized PSMA-Positive Prostate Cancer
title_short Incidental Finding of a PSMA-Positive Pancreatic Cancer in a Patient Suffering from a Metastasized PSMA-Positive Prostate Cancer
title_sort incidental finding of a psma positive pancreatic cancer in a patient suffering from a metastasized psma positive prostate cancer
topic PSMA
pancreatic cancer
PET
url https://www.mdpi.com/2075-4418/11/1/129
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