Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studies
American cutaneous leishmaniasis (ACL) is a major public health problem caused by vector-borne protozoan intracellular parasites from the genus Leishmania, subgenera Viannia and Leishmania. Asymptomatic infection is the most common outcome after Leishmania inoculation. There is incomplete knowledge...
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
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| Series: | Memorias do Instituto Oswaldo Cruz |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016001000599&lng=en&tlng=en |
| _version_ | 1797703036986982400 |
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| author | Fernando J Andrade-Narvaez Elsy Nalleli Loría-Cervera Erika I Sosa-Bibiano Nicole R Van Wynsberghe |
| author_facet | Fernando J Andrade-Narvaez Elsy Nalleli Loría-Cervera Erika I Sosa-Bibiano Nicole R Van Wynsberghe |
| author_sort | Fernando J Andrade-Narvaez |
| collection | DOAJ |
| description | American cutaneous leishmaniasis (ACL) is a major public health problem caused by vector-borne protozoan intracellular parasites from the genus Leishmania, subgenera Viannia and Leishmania. Asymptomatic infection is the most common outcome after Leishmania inoculation. There is incomplete knowledge of the biological processes explaining the absence of signs or symptoms in most cases while other cases present a variety of clinical findings. Most studies of asymptomatic infection have been conducted in areas of endemic visceral leishmaniasis. In contrast, asymptomatic ACL infection has been neglected. This review is focused on the following: (1) epidemiological studies supporting the existence of asymptomatic ACL infection and (2) immunological studies conducted to understand the mechanisms responsible for controlling the parasite and avoiding tissue damage. |
| first_indexed | 2024-03-12T04:58:36Z |
| format | Article |
| id | doaj.art-4dfc4aff19cc4af68c05f59b09ed3ef1 |
| institution | Directory Open Access Journal |
| issn | 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T04:58:36Z |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-4dfc4aff19cc4af68c05f59b09ed3ef12023-09-03T09:14:29ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz1678-80601111059960410.1590/0074-02760160138S0074-02762016001000599Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studiesFernando J Andrade-NarvaezElsy Nalleli Loría-CerveraErika I Sosa-BibianoNicole R Van WynsbergheAmerican cutaneous leishmaniasis (ACL) is a major public health problem caused by vector-borne protozoan intracellular parasites from the genus Leishmania, subgenera Viannia and Leishmania. Asymptomatic infection is the most common outcome after Leishmania inoculation. There is incomplete knowledge of the biological processes explaining the absence of signs or symptoms in most cases while other cases present a variety of clinical findings. Most studies of asymptomatic infection have been conducted in areas of endemic visceral leishmaniasis. In contrast, asymptomatic ACL infection has been neglected. This review is focused on the following: (1) epidemiological studies supporting the existence of asymptomatic ACL infection and (2) immunological studies conducted to understand the mechanisms responsible for controlling the parasite and avoiding tissue damage.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016001000599&lng=en&tlng=enAmerican cutaneous leishmaniasisasymptomatic infection |
| spellingShingle | Fernando J Andrade-Narvaez Elsy Nalleli Loría-Cervera Erika I Sosa-Bibiano Nicole R Van Wynsberghe Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studies Memorias do Instituto Oswaldo Cruz American cutaneous leishmaniasis asymptomatic infection |
| title | Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studies |
| title_full | Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studies |
| title_fullStr | Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studies |
| title_full_unstemmed | Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studies |
| title_short | Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studies |
| title_sort | asymptomatic infection with american cutaneous leishmaniasis epidemiological and immunological studies |
| topic | American cutaneous leishmaniasis asymptomatic infection |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016001000599&lng=en&tlng=en |
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