The clinical heterogeneity of RUNX1 associated familial platelet disorder with predisposition to myeloid malignancy – A case series and review of the literature

The clinical heterogeneity of RUNX1 associated familial platelet disorder with predisposition to myeloid malignancy – A case series and review of the literature

Abstract Germline mutations of runt‐related transcription factor‐1 (RUNX1) cause familial platelet disorder with predisposition to myeloid malignancy (FPDMM), most commonly associated with thrombocytopenia and propensity to develop myeloid neoplasms. A key clinical question is which patients with a...

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Bibliographic Details
Main Authors: Catherine Tang, David J. Rabbolini, Marie‐Christine Morel‐Kopp, David E. Connor, Philip Crispin, Christopher M. Ward, William S. Stevenson
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
familial platelet disorder
familial platelet disorder with predisposition to myeloid malignancy
hereditary myeloid malignancy
inherited thrombocytopenia
RUNX1
Online Access:https://doi.org/10.1002/rth2.12282

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