Male Androgenetic Alopecia : Response To Finasteride
Androgenetic alopecia (AGA) is one of the most common causes of hair loss in genetically predisposed men and women. We studied the therapeutic efficacy and safety of oral finasteride in male patients with AGA. A total of 40 male AGA patients, 18-35 years of age, wad enrolled in the study for a perio...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2004-01-01
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| Series: | Indian Journal of Dermatology |
| Online Access: | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2004;volume=49;issue=3;spage=123;epage=127;aulast=Thakkar;type=0 |
| _version_ | 1819013893748424704 |
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| author | Thakkar Suruchi Reddy B. S. N |
| author_facet | Thakkar Suruchi Reddy B. S. N |
| author_sort | Thakkar Suruchi |
| collection | DOAJ |
| description | Androgenetic alopecia (AGA) is one of the most common causes of hair loss in genetically predisposed men and women. We studied the therapeutic efficacy and safety of oral finasteride in male patients with AGA. A total of 40 male AGA patients, 18-35 years of age, wad enrolled in the study for a period of 9 months. Oral finasteride, 1mg/day, was started and the drug efficacy was assessed on the basis of pre- and post-treatment clinical photographs, trichogram, hair pull test and self assessment of hair re-growth by the investigators. Routine hematological and bio-chemical investigations and a questionnaire related to sexual disturbances were carried out to assess the safety profile of the drug at each follow-up visit every three months. Improvement in hair growth was observed by comparing the paired pre- and post-treatment global photographs (p<0.05), decreased hair shedding by the patients†self assessment (p<0.05), hair pull test evaluation (p<0.001) and increase in anagen-telogen hair ratio (p<0.001) with the trichogram, as early as 3 months of finasteride therapy with maximum benefit in the mid-area followed by vertex and frontal areas. No significant side effect related to the drug was observed. It is concluded that oral finasteride is a relatively safe, well tolerated and efficacious drug for AGA in Males. |
| first_indexed | 2024-12-21T02:07:11Z |
| format | Article |
| id | doaj.art-4dff456f24d1403fa10013e244f3801f |
| institution | Directory Open Access Journal |
| issn | 0019-5154 1998-3611 |
| language | English |
| last_indexed | 2024-12-21T02:07:11Z |
| publishDate | 2004-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Dermatology |
| spelling | doaj.art-4dff456f24d1403fa10013e244f3801f2022-12-21T19:19:28ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36112004-01-01493123127Male Androgenetic Alopecia : Response To FinasterideThakkar SuruchiReddy B. S. NAndrogenetic alopecia (AGA) is one of the most common causes of hair loss in genetically predisposed men and women. We studied the therapeutic efficacy and safety of oral finasteride in male patients with AGA. A total of 40 male AGA patients, 18-35 years of age, wad enrolled in the study for a period of 9 months. Oral finasteride, 1mg/day, was started and the drug efficacy was assessed on the basis of pre- and post-treatment clinical photographs, trichogram, hair pull test and self assessment of hair re-growth by the investigators. Routine hematological and bio-chemical investigations and a questionnaire related to sexual disturbances were carried out to assess the safety profile of the drug at each follow-up visit every three months. Improvement in hair growth was observed by comparing the paired pre- and post-treatment global photographs (p<0.05), decreased hair shedding by the patients†self assessment (p<0.05), hair pull test evaluation (p<0.001) and increase in anagen-telogen hair ratio (p<0.001) with the trichogram, as early as 3 months of finasteride therapy with maximum benefit in the mid-area followed by vertex and frontal areas. No significant side effect related to the drug was observed. It is concluded that oral finasteride is a relatively safe, well tolerated and efficacious drug for AGA in Males.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2004;volume=49;issue=3;spage=123;epage=127;aulast=Thakkar;type=0 |
| spellingShingle | Thakkar Suruchi Reddy B. S. N Male Androgenetic Alopecia : Response To Finasteride Indian Journal of Dermatology |
| title | Male Androgenetic Alopecia : Response To Finasteride |
| title_full | Male Androgenetic Alopecia : Response To Finasteride |
| title_fullStr | Male Androgenetic Alopecia : Response To Finasteride |
| title_full_unstemmed | Male Androgenetic Alopecia : Response To Finasteride |
| title_short | Male Androgenetic Alopecia : Response To Finasteride |
| title_sort | male androgenetic alopecia response to finasteride |
| url | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2004;volume=49;issue=3;spage=123;epage=127;aulast=Thakkar;type=0 |
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