Re-Emergence of Yellow Fever in Brazil during 2016–2019: Challenges, Lessons Learned, and Perspectives
Yellow fever (YF) is a re-emerging viral zoonosis caused by the <i>Yellow Fever virus</i> (YFV), affecting humans and non-human primates (NHP). YF is endemic in South America and Africa, being considered a burden for public health worldwide despite the availability of an effective vaccin...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-10-01
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| Series: | Viruses |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4915/12/11/1233 |
| _version_ | 1797549310288592896 |
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| author | Poliana de Oliveira Figueiredo Ana Gabriella Stoffella-Dutra Galileu Barbosa Costa Jaqueline Silva de Oliveira Carolina Dourado Amaral Juliane Duarte Santos Kamila Lorene Soares Rocha João Pessoa Araújo Júnior Maurício Lacerda Nogueira Magno Augusto Zazá Borges Adriano Pereira Paglia Angelle Desiree LaBeaud Jônatas Santos Abrahão Erna Geessien Kroon Danilo Bretas de Oliveira Betânia Paiva Drumond Giliane de Souza Trindade |
| author_facet | Poliana de Oliveira Figueiredo Ana Gabriella Stoffella-Dutra Galileu Barbosa Costa Jaqueline Silva de Oliveira Carolina Dourado Amaral Juliane Duarte Santos Kamila Lorene Soares Rocha João Pessoa Araújo Júnior Maurício Lacerda Nogueira Magno Augusto Zazá Borges Adriano Pereira Paglia Angelle Desiree LaBeaud Jônatas Santos Abrahão Erna Geessien Kroon Danilo Bretas de Oliveira Betânia Paiva Drumond Giliane de Souza Trindade |
| author_sort | Poliana de Oliveira Figueiredo |
| collection | DOAJ |
| description | Yellow fever (YF) is a re-emerging viral zoonosis caused by the <i>Yellow Fever virus</i> (YFV), affecting humans and non-human primates (NHP). YF is endemic in South America and Africa, being considered a burden for public health worldwide despite the availability of an effective vaccine. Acute infectious disease can progress to severe hemorrhagic conditions and has high rates of morbidity and mortality in endemic countries. In 2016, Brazil started experiencing one of the most significant YF epidemics in its history, with lots of deaths being reported in regions that were previously considered free of the disease. Here, we reviewed the historical aspects of YF in Brazil, the epidemiology of the disease, the challenges that remain in Brazil’s public health context, the main lessons learned from the recent outbreaks, and our perspective for facing future YF epidemics. |
| first_indexed | 2024-03-10T15:12:52Z |
| format | Article |
| id | doaj.art-4e0ab02303bf4b3dbeb8fd1b53811700 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-10T15:12:52Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-4e0ab02303bf4b3dbeb8fd1b538117002023-11-20T19:11:09ZengMDPI AGViruses1999-49152020-10-011211123310.3390/v12111233Re-Emergence of Yellow Fever in Brazil during 2016–2019: Challenges, Lessons Learned, and PerspectivesPoliana de Oliveira Figueiredo0Ana Gabriella Stoffella-Dutra1Galileu Barbosa Costa2Jaqueline Silva de Oliveira3Carolina Dourado Amaral4Juliane Duarte Santos5Kamila Lorene Soares Rocha6João Pessoa Araújo Júnior7Maurício Lacerda Nogueira8Magno Augusto Zazá Borges9Adriano Pereira Paglia10Angelle Desiree LaBeaud11Jônatas Santos Abrahão12Erna Geessien Kroon13Danilo Bretas de Oliveira14Betânia Paiva Drumond15Giliane de Souza Trindade16Laboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, BrazilLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, BrazilLaboratório de Patologia e Biologia Molecular, Instituto Gonçalo Moniz, Oswaldo Cruz Foundation, Rua Waldemar Falcão, 121, Candeal, Salvador Bahia 40296-710, BrazilLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, BrazilLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, BrazilCentro Integrado de Pesquisa em Saúde, Faculdade de Medicina, Universidade Federal dos Vales do Jequitinhonha e Mucuri Campus JK, Diamantina, Minas Gerais, Rodovia MGT 367, Km 583, nº 5.000 Alto da Jacuba 39100-000, BrazilCentro Integrado de Pesquisa em Saúde, Faculdade de Medicina, Universidade Federal dos Vales do Jequitinhonha e Mucuri Campus JK, Diamantina, Minas Gerais, Rodovia MGT 367, Km 583, nº 5.000 Alto da Jacuba 39100-000, BrazilDepartamento de Microbiologia e Imunologia, Institute of Biotechnology, Universidade Estadual Paulista Júlio de Mesquita Filho, Rio Claro, São Paulo Avenida 24A, 1515, Bela Vista 13506-900, BrazilLaboratório de Pesquisas em Virologia, Departamento de Doenças Infecciosas e Parasitárias, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, São Paulo 15090-000, BrazilCentro de Ciências Biológicas e da Saúde, Universidade Estadual de Montes Claros, Montes Claros, Minas Gerais, Avenida Prof. Rui Braga, s/n, Vila Mauriceia 39408-354, BrazilLaboratório de Ecologia e Conservação, Departamento de Biologia Geral, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, BrazilDepartment of Pediatrics, Division of Infectious Diseases, Stanford University School of Medicine, 300 Pasteur Dr Rm G312 MC 5208, Stanford, CA 94305, USALaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, BrazilLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, BrazilCentro Integrado de Pesquisa em Saúde, Faculdade de Medicina, Universidade Federal dos Vales do Jequitinhonha e Mucuri Campus JK, Diamantina, Minas Gerais, Rodovia MGT 367, Km 583, nº 5.000 Alto da Jacuba 39100-000, BrazilLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, BrazilLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, BrazilYellow fever (YF) is a re-emerging viral zoonosis caused by the <i>Yellow Fever virus</i> (YFV), affecting humans and non-human primates (NHP). YF is endemic in South America and Africa, being considered a burden for public health worldwide despite the availability of an effective vaccine. Acute infectious disease can progress to severe hemorrhagic conditions and has high rates of morbidity and mortality in endemic countries. In 2016, Brazil started experiencing one of the most significant YF epidemics in its history, with lots of deaths being reported in regions that were previously considered free of the disease. Here, we reviewed the historical aspects of YF in Brazil, the epidemiology of the disease, the challenges that remain in Brazil’s public health context, the main lessons learned from the recent outbreaks, and our perspective for facing future YF epidemics.https://www.mdpi.com/1999-4915/12/11/1233yellow feverepidemicepidemiologyecologypublic healthBrazil |
| spellingShingle | Poliana de Oliveira Figueiredo Ana Gabriella Stoffella-Dutra Galileu Barbosa Costa Jaqueline Silva de Oliveira Carolina Dourado Amaral Juliane Duarte Santos Kamila Lorene Soares Rocha João Pessoa Araújo Júnior Maurício Lacerda Nogueira Magno Augusto Zazá Borges Adriano Pereira Paglia Angelle Desiree LaBeaud Jônatas Santos Abrahão Erna Geessien Kroon Danilo Bretas de Oliveira Betânia Paiva Drumond Giliane de Souza Trindade Re-Emergence of Yellow Fever in Brazil during 2016–2019: Challenges, Lessons Learned, and Perspectives Viruses yellow fever epidemic epidemiology ecology public health Brazil |
| title | Re-Emergence of Yellow Fever in Brazil during 2016–2019: Challenges, Lessons Learned, and Perspectives |
| title_full | Re-Emergence of Yellow Fever in Brazil during 2016–2019: Challenges, Lessons Learned, and Perspectives |
| title_fullStr | Re-Emergence of Yellow Fever in Brazil during 2016–2019: Challenges, Lessons Learned, and Perspectives |
| title_full_unstemmed | Re-Emergence of Yellow Fever in Brazil during 2016–2019: Challenges, Lessons Learned, and Perspectives |
| title_short | Re-Emergence of Yellow Fever in Brazil during 2016–2019: Challenges, Lessons Learned, and Perspectives |
| title_sort | re emergence of yellow fever in brazil during 2016 2019 challenges lessons learned and perspectives |
| topic | yellow fever epidemic epidemiology ecology public health Brazil |
| url | https://www.mdpi.com/1999-4915/12/11/1233 |
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