HDAC3 promotes macrophage pyroptosis via regulating histone deacetylation in acute lung injury

HDAC3 promotes macrophage pyroptosis via regulating histone deacetylation in acute lung injury

Summary: Activated inflammation and pyroptosis in macrophage are closely associated with acute lung injury (ALI). Histone deacetylase 3 (HDAC3) serves as an important enzyme that could repress gene expression by mediating chromatin remodeling. In this study, we found that HDAC3 was highly expressed...

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Bibliographic Details
Main Authors: Ning Li, Bohao Liu, Ruyuan He, Guorui Li, Rui Xiong, Tinglv Fu, Donghang Li, Chenzhen Xu, Bo Wang, Qing Geng
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Biochemistry
Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422301235X

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