Effect of Smoking Cessation on Left Ventricular Ejection Fraction after Acute ST Elevation Myocardial Infarction
BACKGROUND: Acute Myocardial Infarction (AMI) is the leading cause of global mortality. Moreover, Left Ventricular Ejection Fraction (LVEF) is the most important predictor of post-AMI mortality. Thus, the present study aimed to investigate the relationship between smoking cessation and LVEF followin...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Vesnu Publications
2023-03-01
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| Series: | ARYA Atherosclerosis |
| Subjects: | |
| Online Access: | https://arya.mui.ac.ir/article_26189_e6643f32cbabd279afb528e4ca06dc7a.pdf |
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| author | Parisa Janjani Javad Azimivaghar Nahid Salehi Reza Haidari Moghadam Mohammad Shakiba Soraya Siabani Hassan Azarpara Mina Tahmasebi Mohammad Rouzbahani |
| author_facet | Parisa Janjani Javad Azimivaghar Nahid Salehi Reza Haidari Moghadam Mohammad Shakiba Soraya Siabani Hassan Azarpara Mina Tahmasebi Mohammad Rouzbahani |
| author_sort | Parisa Janjani |
| collection | DOAJ |
| description | BACKGROUND: Acute Myocardial Infarction (AMI) is the leading cause of global mortality. Moreover, Left Ventricular Ejection Fraction (LVEF) is the most important predictor of post-AMI mortality. Thus, the present study aimed to investigate the relationship between smoking cessation and LVEF following one year from the STEMI.CASE REPORT: The present study was a part of the Kermanshah STEMI Registry and included 825 smokers admitted to Imam Ali Hospital, Kermanshah, Iran, with AMI during a 2-year study period. Data collection was performed using the standardized case report form by the European Observational Registry Program (EORP). Moreover, multiple logistic regression was used to compare LVEF between the patients who had quit smoking post-AMI and those who were still smokers after one year. Also, one-to-one Propensity Score Matching (PSM) was used to reduce the assessment error and selection bias, increase the result accuracy, and minimize the effects of confounders on the LVEF-smoking relationship.Results: Following one year after AMI, 219 (26.55%) patients had quit smoking, while 606 (73.45%) still smoked. Using the PSM, a total of 168 ex-smokers were matched to 168 current smokers. Moreover, it was shown that LVEF was higher in current smokers compared to ex-smokers. However, the difference was not significant. Also, multiple logistic regression showed that the Odds Ratio (OR) of LVEF reduction was insignificantly higher in ex-smokers (OR=1.13; 95% CI: 0.98-1.29) compared to current smokers. Multivariate regression analysis found similar results even after the application of PSM (OR 1.02; 95% CI: 0.82-1.22).CONCLUSIONS: Given the low rate of smoking cessation after MI, physicians are recommended to ask about the smoking status of MI patients at each office visit or re-admission and strongly recommend quitting smoking. |
| first_indexed | 2024-03-12T00:04:04Z |
| format | Article |
| id | doaj.art-4e0e562b01a04c6995c97f8b24272895 |
| institution | Directory Open Access Journal |
| issn | 1735-3955 2251-6638 |
| language | English |
| last_indexed | 2024-03-12T00:04:04Z |
| publishDate | 2023-03-01 |
| publisher | Vesnu Publications |
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| series | ARYA Atherosclerosis |
| spelling | doaj.art-4e0e562b01a04c6995c97f8b242728952023-09-17T06:27:11ZengVesnu PublicationsARYA Atherosclerosis1735-39552251-66382023-03-0119Issue 3707610.48305/ARYA.2022.11895.273426189Effect of Smoking Cessation on Left Ventricular Ejection Fraction after Acute ST Elevation Myocardial InfarctionParisa Janjani0Javad Azimivaghar1Nahid Salehi2Reza Haidari Moghadam3Mohammad Shakiba4Soraya Siabani5Hassan Azarpara6Mina Tahmasebi7Mohammad Rouzbahani8Cardiovascular Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.Cardiovascular Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.Cardiovascular Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.Cardiovascular Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.Cardiovascular Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.Cardiovascular Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.Cardiovascular Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.Cardiovascular Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.Cardiovascular Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.BACKGROUND: Acute Myocardial Infarction (AMI) is the leading cause of global mortality. Moreover, Left Ventricular Ejection Fraction (LVEF) is the most important predictor of post-AMI mortality. Thus, the present study aimed to investigate the relationship between smoking cessation and LVEF following one year from the STEMI.CASE REPORT: The present study was a part of the Kermanshah STEMI Registry and included 825 smokers admitted to Imam Ali Hospital, Kermanshah, Iran, with AMI during a 2-year study period. Data collection was performed using the standardized case report form by the European Observational Registry Program (EORP). Moreover, multiple logistic regression was used to compare LVEF between the patients who had quit smoking post-AMI and those who were still smokers after one year. Also, one-to-one Propensity Score Matching (PSM) was used to reduce the assessment error and selection bias, increase the result accuracy, and minimize the effects of confounders on the LVEF-smoking relationship.Results: Following one year after AMI, 219 (26.55%) patients had quit smoking, while 606 (73.45%) still smoked. Using the PSM, a total of 168 ex-smokers were matched to 168 current smokers. Moreover, it was shown that LVEF was higher in current smokers compared to ex-smokers. However, the difference was not significant. Also, multiple logistic regression showed that the Odds Ratio (OR) of LVEF reduction was insignificantly higher in ex-smokers (OR=1.13; 95% CI: 0.98-1.29) compared to current smokers. Multivariate regression analysis found similar results even after the application of PSM (OR 1.02; 95% CI: 0.82-1.22).CONCLUSIONS: Given the low rate of smoking cessation after MI, physicians are recommended to ask about the smoking status of MI patients at each office visit or re-admission and strongly recommend quitting smoking.https://arya.mui.ac.ir/article_26189_e6643f32cbabd279afb528e4ca06dc7a.pdfmyocardial infarctionregistryiranleft ventricular ejection fractionsmoking cessation |
| spellingShingle | Parisa Janjani Javad Azimivaghar Nahid Salehi Reza Haidari Moghadam Mohammad Shakiba Soraya Siabani Hassan Azarpara Mina Tahmasebi Mohammad Rouzbahani Effect of Smoking Cessation on Left Ventricular Ejection Fraction after Acute ST Elevation Myocardial Infarction ARYA Atherosclerosis myocardial infarction registry iran left ventricular ejection fraction smoking cessation |
| title | Effect of Smoking Cessation on Left Ventricular Ejection Fraction after Acute ST Elevation Myocardial Infarction |
| title_full | Effect of Smoking Cessation on Left Ventricular Ejection Fraction after Acute ST Elevation Myocardial Infarction |
| title_fullStr | Effect of Smoking Cessation on Left Ventricular Ejection Fraction after Acute ST Elevation Myocardial Infarction |
| title_full_unstemmed | Effect of Smoking Cessation on Left Ventricular Ejection Fraction after Acute ST Elevation Myocardial Infarction |
| title_short | Effect of Smoking Cessation on Left Ventricular Ejection Fraction after Acute ST Elevation Myocardial Infarction |
| title_sort | effect of smoking cessation on left ventricular ejection fraction after acute st elevation myocardial infarction |
| topic | myocardial infarction registry iran left ventricular ejection fraction smoking cessation |
| url | https://arya.mui.ac.ir/article_26189_e6643f32cbabd279afb528e4ca06dc7a.pdf |
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