Shrew-borne hantaviruses (Hantaviridae: <i>Orthohantavirus</i>) in the Far East of Russia
Introduction. Insectivores are newly recognized hantaviral reservoir worldwide. Four distinct shrew-borne hantaviruses (family Hantaviridae) have been identified in two regions located in southern and northern part of the Russian Far East, two genetic variants of Seewis virus (SWSV), Lena River viru...
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| Format: | Article |
| Language: | English |
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Central Research Institute for Epidemiology
2023-03-01
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| Series: | Вопросы вирусологии |
| Subjects: | |
| Online Access: | https://virusjour.crie.ru/jour/article/viewFile/6313/439 |
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| author | L. N. Yashina L. I. Ivanov G. G. Kompanets N. I. Zdanovskaya M. Yu. Kartashov |
| author_facet | L. N. Yashina L. I. Ivanov G. G. Kompanets N. I. Zdanovskaya M. Yu. Kartashov |
| author_sort | L. N. Yashina |
| collection | DOAJ |
| description | Introduction. Insectivores are newly recognized hantaviral reservoir worldwide. Four distinct shrew-borne hantaviruses (family Hantaviridae) have been identified in two regions located in southern and northern part of the Russian Far East, two genetic variants of Seewis virus (SWSV), Lena River virus (LENV), Kenkeme virus (KKMV) and Yakeshi virus (YKSV). Here, we describe geographic distribution of shrew-borne hantaviruses in southern part of the Russian Far East: Jewish Autonomous region, Khabarovsk Krai, Primorsky Krai and Sakhalin region.
Materials and methods. Lung samples from shrews of genus Sorex, captured in the four regions of Far Eastern Russia, were examined for hantavirus RNA using reverse transcription polymerase chain reaction (RT-PCR). Phylogenetic analysis of the partial nucleotide sequences of viral genome was conducted using MEGA X software.
Results. New genetic variant of YKSV was identified in new reservoir host, long-clawed shrew (S. ungiuculatus) from Sakhalin Island. Genetic variant of SWSV, ARTV-Sc, has been found to circulate among S. caecutiens on the seacoast of Khabarovsk and Primorsky Krai. KKMV virus and second genetic variant of SWSV, ARTV-St, were found in S. roboratus and S. tundrensis, respectively from Jewish Autonomous region.
Conclusion. Sorex-borne hantaviruses were found in all studied regions of Far Eastern Russia. Our results demonstrated co-evolution of SWSV, KKMV, and YKSV viruses throughout the geographic distribution of its hosts. |
| first_indexed | 2024-03-13T00:08:35Z |
| format | Article |
| id | doaj.art-4e132531b2d8430c91a0643d6bb82e23 |
| institution | Directory Open Access Journal |
| issn | 0507-4088 2411-2097 |
| language | English |
| last_indexed | 2024-03-13T00:08:35Z |
| publishDate | 2023-03-01 |
| publisher | Central Research Institute for Epidemiology |
| record_format | Article |
| series | Вопросы вирусологии |
| spelling | doaj.art-4e132531b2d8430c91a0643d6bb82e232023-07-12T19:31:59ZengCentral Research Institute for EpidemiologyВопросы вирусологии0507-40882411-20972023-03-01681798510.36233/0507-4088-165476Shrew-borne hantaviruses (Hantaviridae: <i>Orthohantavirus</i>) in the Far East of RussiaL. N. Yashina0https://orcid.org/0000-0003-2844-7835L. I. Ivanov1https://orcid.org/0000-0003-0349-837XG. G. Kompanets2https://orcid.org/0000-0001-7315-6119N. I. Zdanovskaya3https://orcid.org/0000-0001-5507-7521M. Yu. Kartashov4https://orcid.org/0000-0002-7857-6822State Research Center of Virology and Biotechnology “VECTOR” of RospotrebnadzorKhabarovsk Antiplague Station of RospotrebnadzorFar Eastern Federal UniversityKhabarovsk Antiplague Station of RospotrebnadzorState Research Center of Virology and Biotechnology “VECTOR” of RospotrebnadzorIntroduction. Insectivores are newly recognized hantaviral reservoir worldwide. Four distinct shrew-borne hantaviruses (family Hantaviridae) have been identified in two regions located in southern and northern part of the Russian Far East, two genetic variants of Seewis virus (SWSV), Lena River virus (LENV), Kenkeme virus (KKMV) and Yakeshi virus (YKSV). Here, we describe geographic distribution of shrew-borne hantaviruses in southern part of the Russian Far East: Jewish Autonomous region, Khabarovsk Krai, Primorsky Krai and Sakhalin region. Materials and methods. Lung samples from shrews of genus Sorex, captured in the four regions of Far Eastern Russia, were examined for hantavirus RNA using reverse transcription polymerase chain reaction (RT-PCR). Phylogenetic analysis of the partial nucleotide sequences of viral genome was conducted using MEGA X software. Results. New genetic variant of YKSV was identified in new reservoir host, long-clawed shrew (S. ungiuculatus) from Sakhalin Island. Genetic variant of SWSV, ARTV-Sc, has been found to circulate among S. caecutiens on the seacoast of Khabarovsk and Primorsky Krai. KKMV virus and second genetic variant of SWSV, ARTV-St, were found in S. roboratus and S. tundrensis, respectively from Jewish Autonomous region. Conclusion. Sorex-borne hantaviruses were found in all studied regions of Far Eastern Russia. Our results demonstrated co-evolution of SWSV, KKMV, and YKSV viruses throughout the geographic distribution of its hosts.https://virusjour.crie.ru/jour/article/viewFile/6313/439hantavirusinsectivoresshrewphylogenetic analysis |
| spellingShingle | L. N. Yashina L. I. Ivanov G. G. Kompanets N. I. Zdanovskaya M. Yu. Kartashov Shrew-borne hantaviruses (Hantaviridae: <i>Orthohantavirus</i>) in the Far East of Russia Вопросы вирусологии hantavirus insectivores shrew phylogenetic analysis |
| title | Shrew-borne hantaviruses (Hantaviridae: <i>Orthohantavirus</i>) in the Far East of Russia |
| title_full | Shrew-borne hantaviruses (Hantaviridae: <i>Orthohantavirus</i>) in the Far East of Russia |
| title_fullStr | Shrew-borne hantaviruses (Hantaviridae: <i>Orthohantavirus</i>) in the Far East of Russia |
| title_full_unstemmed | Shrew-borne hantaviruses (Hantaviridae: <i>Orthohantavirus</i>) in the Far East of Russia |
| title_short | Shrew-borne hantaviruses (Hantaviridae: <i>Orthohantavirus</i>) in the Far East of Russia |
| title_sort | shrew borne hantaviruses hantaviridae i orthohantavirus i in the far east of russia |
| topic | hantavirus insectivores shrew phylogenetic analysis |
| url | https://virusjour.crie.ru/jour/article/viewFile/6313/439 |
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