Curcumin and butyrate induce fibroblast senescence without the emergence of fibrosis biomarkers

Background: Small molecules have emerged as valuable tools to modulate cellular homeostasis and the changes associated with aging. In particular, the phytochemical curcumin elicits cytoprotective effects that promote human health and longevity. The short-chain fatty acid butyrate provides anti-fibro...

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Bibliographic Details
Main Authors: Siwei Chu, Natali Joma, Hui Wen Yong, Dusica Maysinger, Ashok Kakkar, Ursula Stochaj
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Aspects of Molecular Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2949688823000217