Native N-glycome profiling of single cells and ng-level blood isolates using label-free capillary electrophoresis-mass spectrometry
Abstract The development of reliable single-cell dispensers and substantial sensitivity improvement in mass spectrometry made proteomic profiling of individual cells achievable. Yet, there are no established methods for single-cell glycome analysis due to the inability to amplify glycans and sample...
| Hauptverfasser: | , , |
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| Format: | Artikel |
| Sprache: | English |
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Nature Portfolio
2024-05-01
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| Schriftenreihe: | Nature Communications |
| Online Zugang: | https://doi.org/10.1038/s41467-024-47772-w |