Native N-glycome profiling of single cells and ng-level blood isolates using label-free capillary electrophoresis-mass spectrometry

Abstract The development of reliable single-cell dispensers and substantial sensitivity improvement in mass spectrometry made proteomic profiling of individual cells achievable. Yet, there are no established methods for single-cell glycome analysis due to the inability to amplify glycans and sample...

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Détails bibliographiques
Auteurs principaux: Anne-Lise Marie, Yunfan Gao, Alexander R. Ivanov
Format: Article
Langue:English
Publié: Nature Portfolio 2024-05-01
Collection:Nature Communications
Accès en ligne:https://doi.org/10.1038/s41467-024-47772-w