N6-methyladenosine (m6A) methyltransferase METTL3-mediated LINC00680 accelerates osteoarthritis through m6A/SIRT1 manner
LINC00680/m6A/IGF2BP2/SIRT1 axis promotes the OA progression in chondrocyte.
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2022-05-01
|
| Series: | Cell Death Discovery |
| Online Access: | https://doi.org/10.1038/s41420-022-00890-0 |
| _version_ | 1817985380387913728 |
|---|---|
| author | Jiangdong Ren Yicheng Li Shalitanati Wuermanbieke Shu Hu Guangxin Huang |
| author_facet | Jiangdong Ren Yicheng Li Shalitanati Wuermanbieke Shu Hu Guangxin Huang |
| author_sort | Jiangdong Ren |
| collection | DOAJ |
| description | LINC00680/m6A/IGF2BP2/SIRT1 axis promotes the OA progression in chondrocyte. |
| first_indexed | 2024-04-13T23:56:26Z |
| format | Article |
| id | doaj.art-4e195f983e53456f9613ed9391ca8ea5 |
| institution | Directory Open Access Journal |
| issn | 2058-7716 |
| language | English |
| last_indexed | 2024-04-13T23:56:26Z |
| publishDate | 2022-05-01 |
| publisher | Nature Publishing Group |
| record_format | Article |
| series | Cell Death Discovery |
| spelling | doaj.art-4e195f983e53456f9613ed9391ca8ea52022-12-22T02:23:51ZengNature Publishing GroupCell Death Discovery2058-77162022-05-01811810.1038/s41420-022-00890-0N6-methyladenosine (m6A) methyltransferase METTL3-mediated LINC00680 accelerates osteoarthritis through m6A/SIRT1 mannerJiangdong Ren0Yicheng Li1Shalitanati Wuermanbieke2Shu Hu3Guangxin Huang4Department of Joint Surgery, Center for Orthopaedics Surgery, The Third Affiliated Hospital of Southern Medical University (Academy of Orthopaedics Guangdong Province)Department of Orthopaedics, First Affiliated Hospital of Xinjiang Medical UniversityKaramay Central HospitalDepartment of Joint Surgery, Center for Orthopaedics Surgery, The Third Affiliated Hospital of Southern Medical University (Academy of Orthopaedics Guangdong Province)Department of Joint Surgery, Center for Orthopaedics Surgery, The Third Affiliated Hospital of Southern Medical University (Academy of Orthopaedics Guangdong Province)LINC00680/m6A/IGF2BP2/SIRT1 axis promotes the OA progression in chondrocyte.https://doi.org/10.1038/s41420-022-00890-0 |
| spellingShingle | Jiangdong Ren Yicheng Li Shalitanati Wuermanbieke Shu Hu Guangxin Huang N6-methyladenosine (m6A) methyltransferase METTL3-mediated LINC00680 accelerates osteoarthritis through m6A/SIRT1 manner Cell Death Discovery |
| title | N6-methyladenosine (m6A) methyltransferase METTL3-mediated LINC00680 accelerates osteoarthritis through m6A/SIRT1 manner |
| title_full | N6-methyladenosine (m6A) methyltransferase METTL3-mediated LINC00680 accelerates osteoarthritis through m6A/SIRT1 manner |
| title_fullStr | N6-methyladenosine (m6A) methyltransferase METTL3-mediated LINC00680 accelerates osteoarthritis through m6A/SIRT1 manner |
| title_full_unstemmed | N6-methyladenosine (m6A) methyltransferase METTL3-mediated LINC00680 accelerates osteoarthritis through m6A/SIRT1 manner |
| title_short | N6-methyladenosine (m6A) methyltransferase METTL3-mediated LINC00680 accelerates osteoarthritis through m6A/SIRT1 manner |
| title_sort | n6 methyladenosine m6a methyltransferase mettl3 mediated linc00680 accelerates osteoarthritis through m6a sirt1 manner |
| url | https://doi.org/10.1038/s41420-022-00890-0 |
| work_keys_str_mv | AT jiangdongren n6methyladenosinem6amethyltransferasemettl3mediatedlinc00680acceleratesosteoarthritisthroughm6asirt1manner AT yichengli n6methyladenosinem6amethyltransferasemettl3mediatedlinc00680acceleratesosteoarthritisthroughm6asirt1manner AT shalitanatiwuermanbieke n6methyladenosinem6amethyltransferasemettl3mediatedlinc00680acceleratesosteoarthritisthroughm6asirt1manner AT shuhu n6methyladenosinem6amethyltransferasemettl3mediatedlinc00680acceleratesosteoarthritisthroughm6asirt1manner AT guangxinhuang n6methyladenosinem6amethyltransferasemettl3mediatedlinc00680acceleratesosteoarthritisthroughm6asirt1manner |