Modification of the Gastric Mucosal Microbiota by a Strain-Specific <named-content content-type="genus-species">Helicobacter pylori</named-content> Oncoprotein and Carcinogenic Histologic Phenotype

Modification of the Gastric Mucosal Microbiota by a Strain-Specific <named-content content-type="genus-species">Helicobacter pylori</named-content> Oncoprotein and Carcinogenic Histologic Phenotype

ABSTRACT Helicobacter pylori is the strongest risk factor for gastric adenocarcinoma; however, most infected individuals never develop this malignancy. Strain-specific microbial factors, such as the oncoprotein CagA, as well as environmental conditions, such as iron deficiency, augment cancer risk....

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Bibliographic Details
Main Authors: Jennifer M. Noto, Joseph P. Zackular, Matthew G. Varga, Alberto Delgado, Judith Romero-Gallo, Matthew B. Scholz, M. Blanca Piazuelo, Eric P. Skaar, Richard M. Peek
Format: Article
Language:English
Published: American Society for Microbiology 2019-06-01
Series:mBio
Subjects:
CagA
Helicobacter pylori
gastric cancer
gastric microbiota
iron deficiency
Online Access:https://journals.asm.org/doi/10.1128/mBio.00955-19

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