Age at first childbirth and the risk of hypertriglyceridemia among Korean women
OBJECTIVES We aimed to investigate the association of age at first childbirth with the risk of hypertriglyceridemia among Korean women. METHODS This study used data from the Korean Genome and Epidemiology Study–Cardiovascular Disease Association Study. In total, 16,747 women were included in the cro...
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| Format: | Article |
| Language: | English |
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Korean Society of Epidemiology
2022-12-01
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| Series: | Epidemiology and Health |
| Subjects: | |
| Online Access: | http://www.e-epih.org/upload/epih-45-e2023010.pdf |
| _version_ | 1797305287998177280 |
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| author | Hye Rin Choi Hyeon Chang Kim |
| author_facet | Hye Rin Choi Hyeon Chang Kim |
| author_sort | Hye Rin Choi |
| collection | DOAJ |
| description | OBJECTIVES We aimed to investigate the association of age at first childbirth with the risk of hypertriglyceridemia among Korean women. METHODS This study used data from the Korean Genome and Epidemiology Study–Cardiovascular Disease Association Study. In total, 16,747 women were included in the cross-sectional analysis, and 6,250 women were included in the longitudinal analysis. The participants were divided based on their age at first childbirth (<20, 20-24, 25-29, and ≥30 years). Hypertriglyceridemia was defined as triglyceride levels of ≥150 mg/dL. RESULTS The multivariable-adjusted odds ratio for prevalent hypertriglyceridemia was 1.19 (95% confidence interval [CI], 1.01 to 1.40) in women whose first childbirth was before 20 years of age, compared to those whose first childbirth was at 25-29 years of age, after adjustment for age, study site, body mass index, blood pressure, diabetes, alcohol consumption, carbohydrate intake, income, marital status, education, parity, usage of oral contraceptives, and hormone replacement status. During a median follow-up of 5.2 years, 1,770 women developed hypertriglyceridemia. Compared with women who gave birth to their first child between 25 years and 29 years of age, those giving birth to their first child before 20 years of age had a higher risk for incident hypertriglyceridemia in later life (adjusted hazard ratio, 1.25; 95% CI, 0.99 to 1.57). CONCLUSIONS Giving birth to one’s first child before the age of 20 years was associated with an increased risk of hypertriglyceridemia among Korean women. |
| first_indexed | 2024-03-08T00:24:47Z |
| format | Article |
| id | doaj.art-4e20bccb5c4f4a05850382299321ac3e |
| institution | Directory Open Access Journal |
| issn | 2092-7193 |
| language | English |
| last_indexed | 2024-03-08T00:24:47Z |
| publishDate | 2022-12-01 |
| publisher | Korean Society of Epidemiology |
| record_format | Article |
| series | Epidemiology and Health |
| spelling | doaj.art-4e20bccb5c4f4a05850382299321ac3e2024-02-16T01:04:24ZengKorean Society of EpidemiologyEpidemiology and Health2092-71932022-12-014510.4178/epih.e20230101371Age at first childbirth and the risk of hypertriglyceridemia among Korean womenHye Rin Choi0Hyeon Chang Kim1 Center for Cohort Studies, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, KoreaOBJECTIVES We aimed to investigate the association of age at first childbirth with the risk of hypertriglyceridemia among Korean women. METHODS This study used data from the Korean Genome and Epidemiology Study–Cardiovascular Disease Association Study. In total, 16,747 women were included in the cross-sectional analysis, and 6,250 women were included in the longitudinal analysis. The participants were divided based on their age at first childbirth (<20, 20-24, 25-29, and ≥30 years). Hypertriglyceridemia was defined as triglyceride levels of ≥150 mg/dL. RESULTS The multivariable-adjusted odds ratio for prevalent hypertriglyceridemia was 1.19 (95% confidence interval [CI], 1.01 to 1.40) in women whose first childbirth was before 20 years of age, compared to those whose first childbirth was at 25-29 years of age, after adjustment for age, study site, body mass index, blood pressure, diabetes, alcohol consumption, carbohydrate intake, income, marital status, education, parity, usage of oral contraceptives, and hormone replacement status. During a median follow-up of 5.2 years, 1,770 women developed hypertriglyceridemia. Compared with women who gave birth to their first child between 25 years and 29 years of age, those giving birth to their first child before 20 years of age had a higher risk for incident hypertriglyceridemia in later life (adjusted hazard ratio, 1.25; 95% CI, 0.99 to 1.57). CONCLUSIONS Giving birth to one’s first child before the age of 20 years was associated with an increased risk of hypertriglyceridemia among Korean women.http://www.e-epih.org/upload/epih-45-e2023010.pdfchildbirthparturitionhypertriglyceridemiatriglycerides |
| spellingShingle | Hye Rin Choi Hyeon Chang Kim Age at first childbirth and the risk of hypertriglyceridemia among Korean women Epidemiology and Health childbirth parturition hypertriglyceridemia triglycerides |
| title | Age at first childbirth and the risk of hypertriglyceridemia among Korean women |
| title_full | Age at first childbirth and the risk of hypertriglyceridemia among Korean women |
| title_fullStr | Age at first childbirth and the risk of hypertriglyceridemia among Korean women |
| title_full_unstemmed | Age at first childbirth and the risk of hypertriglyceridemia among Korean women |
| title_short | Age at first childbirth and the risk of hypertriglyceridemia among Korean women |
| title_sort | age at first childbirth and the risk of hypertriglyceridemia among korean women |
| topic | childbirth parturition hypertriglyceridemia triglycerides |
| url | http://www.e-epih.org/upload/epih-45-e2023010.pdf |
| work_keys_str_mv | AT hyerinchoi ageatfirstchildbirthandtheriskofhypertriglyceridemiaamongkoreanwomen AT hyeonchangkim ageatfirstchildbirthandtheriskofhypertriglyceridemiaamongkoreanwomen |