Target-Oriented Synthesis of Marine Coelenterazine Derivatives with Anticancer Activity by Applying the Heavy-Atom Effect

Target-Oriented Synthesis of Marine Coelenterazine Derivatives with Anticancer Activity by Applying the Heavy-Atom Effect

Photodynamic therapy (PDT) is an anticancer therapeutic modality with remarkable advantages over more conventional approaches. However, PDT is greatly limited by its dependence on external light sources. Given this, PDT would benefit from new systems capable of a light-free and intracellular photody...

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Bibliographic Details
Main Authors: Carla M. Magalhães, Patricia González-Berdullas, Diana Duarte, Ana Salomé Correia, José E. Rodríguez-Borges, Nuno Vale, Joaquim C. G. Esteves da Silva, Luís Pinto da Silva
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomedicines
Subjects:
photodynamic therapy
cancer
coelenterazine
chemiluminescence
heavy-atom effect
triplet chemiexcitation
Online Access:https://www.mdpi.com/2227-9059/9/9/1199

Internet

https://www.mdpi.com/2227-9059/9/9/1199

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