Mechanisms of nucleotide selection by telomerase

Telomerase extends telomere sequences at chromosomal ends to protect genomic DNA. During this process it must select the correct nucleotide from a pool of nucleotides with various sugars and base pairing properties, which is critically important for the proper capping of telomeric sequences by shelt...

Full description

Bibliographic Details
Main Authors: Matthew A Schaich, Samantha L Sanford, Griffin A Welfer, Samuel A Johnson, Thu H Khoang, Patricia L Opresko, Bret D Freudenthal
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/55438