Bile is a reliable and valuable source to study cfDNA in biliary tract cancers

Bile is a reliable and valuable source to study cfDNA in biliary tract cancers

ObjectiveThe aim of this study is to determine the clinical efficacy of bile-derived liquid biopsy compared with plasma and tumor tissue biopsy in patients with biliary tract carcinoma (BTC).MethodsA total of 13 patients with BTC were enrolled in this cohort. Tumor tissue, bile, and plasma samples w...

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Bibliographic Details
Main Authors: Zhanghui Li, Yelei Liu, Junhui Fu, Joseph Mugaanyi, Junrong Yan, Caide Lu, Jing Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
biliary tract carcinoma
bile
next-generation sequencing
chromosomal instability
liquid biopsy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.961939/full

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