Role of the NLRP3 Inflammasome: Insights Into Cancer Hallmarks

Role of the NLRP3 Inflammasome: Insights Into Cancer Hallmarks

In response to a variety of stresses, mammalian cells activate the inflammasome for targeted caspase-dependent pyroptosis. The research community has recently begun to deduce that the activation of inflammasome is instigated by several known oncogenic stresses and metabolic perturbations; neverthele...

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Bibliographic Details
Main Authors: Ting-Yi Lin, Meng-Chun Tsai, Wei Tu, Hsin-Chih Yeh, Shu-Chi Wang, Shu-Pin Huang, Chia-Yang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
NLRP3 inflammasome
cancer hallmarks
tumor microenvironment
pyroptosis
interleukin-1β
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.610492/full

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