Effect on electrospun fibres by synthesis of high branching polylactic acid
Polylactic electrospun porous fibres have been widely used in tissue engineering scaffolds. However, the application of linear polylactic is limited due to its poor hydrophilicity, which leads to phase separation and has been seldom used in porous fibre preparation. Instead, branching polylactic act...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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The Royal Society
2018-01-01
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| Series: | Royal Society Open Science |
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| Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.180134 |
| _version_ | 1828900593122410496 |
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| author | Wen Shen Guanghua Zhang Xuemei Ge Yali Li Guodong Fan |
| author_facet | Wen Shen Guanghua Zhang Xuemei Ge Yali Li Guodong Fan |
| author_sort | Wen Shen |
| collection | DOAJ |
| description | Polylactic electrospun porous fibres have been widely used in tissue engineering scaffolds. However, the application of linear polylactic is limited due to its poor hydrophilicity, which leads to phase separation and has been seldom used in porous fibre preparation. Instead, branching polylactic acts as a new effective method to prepare porous fibres because it can increase polylactic polar property and make it easy to be formulated in the following application. In the current study, we prepared an ultra-high molecular weight of high branching polylactic with glycerol as the initiator by controlling the ring-opening polymerization time, adding amount of catalyst and glycerol. The structure, molecular weight and thermal properties of copolymers were tested subsequently. The result showed that the surface of the high branching polylactic films is smooth, hydrophilic and porous. This branching polylactic formed electrospun porous fibres and possessed a strong adsorption of silver ion. Our study provided a simple and efficient way to synthesize branching polylactic polymer and prepare electrospun porous fibres, which may provide potential applications in the field of biomaterials for tissue engineering or antibacterial dressing compared with the application of linear polylactic and 3-arm polylactic materials. |
| first_indexed | 2024-12-13T15:49:31Z |
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| id | doaj.art-4e332267064b4057a323ee12d890f565 |
| institution | Directory Open Access Journal |
| issn | 2054-5703 |
| language | English |
| last_indexed | 2024-12-13T15:49:31Z |
| publishDate | 2018-01-01 |
| publisher | The Royal Society |
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| series | Royal Society Open Science |
| spelling | doaj.art-4e332267064b4057a323ee12d890f5652022-12-21T23:39:34ZengThe Royal SocietyRoyal Society Open Science2054-57032018-01-015910.1098/rsos.180134180134Effect on electrospun fibres by synthesis of high branching polylactic acidWen ShenGuanghua ZhangXuemei GeYali LiGuodong FanPolylactic electrospun porous fibres have been widely used in tissue engineering scaffolds. However, the application of linear polylactic is limited due to its poor hydrophilicity, which leads to phase separation and has been seldom used in porous fibre preparation. Instead, branching polylactic acts as a new effective method to prepare porous fibres because it can increase polylactic polar property and make it easy to be formulated in the following application. In the current study, we prepared an ultra-high molecular weight of high branching polylactic with glycerol as the initiator by controlling the ring-opening polymerization time, adding amount of catalyst and glycerol. The structure, molecular weight and thermal properties of copolymers were tested subsequently. The result showed that the surface of the high branching polylactic films is smooth, hydrophilic and porous. This branching polylactic formed electrospun porous fibres and possessed a strong adsorption of silver ion. Our study provided a simple and efficient way to synthesize branching polylactic polymer and prepare electrospun porous fibres, which may provide potential applications in the field of biomaterials for tissue engineering or antibacterial dressing compared with the application of linear polylactic and 3-arm polylactic materials.https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.180134high branching plaring opening polymerizationultra-high molecular weighthydrophilicityelectrospunbiomaterials |
| spellingShingle | Wen Shen Guanghua Zhang Xuemei Ge Yali Li Guodong Fan Effect on electrospun fibres by synthesis of high branching polylactic acid Royal Society Open Science high branching pla ring opening polymerization ultra-high molecular weight hydrophilicity electrospun biomaterials |
| title | Effect on electrospun fibres by synthesis of high branching polylactic acid |
| title_full | Effect on electrospun fibres by synthesis of high branching polylactic acid |
| title_fullStr | Effect on electrospun fibres by synthesis of high branching polylactic acid |
| title_full_unstemmed | Effect on electrospun fibres by synthesis of high branching polylactic acid |
| title_short | Effect on electrospun fibres by synthesis of high branching polylactic acid |
| title_sort | effect on electrospun fibres by synthesis of high branching polylactic acid |
| topic | high branching pla ring opening polymerization ultra-high molecular weight hydrophilicity electrospun biomaterials |
| url | https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.180134 |
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