CYRI/ Fam49 Proteins Represent a New Class of Rac1 Interactors

CYRI/ Fam49 Proteins Represent a New Class of Rac1 Interactors

Fam49 proteins, now referred to as CYRI (CYFIP-related Rac Interactor), are evolutionarily conserved across many phyla. Their closest relative by amino acid sequence is CYFIP, as both proteins contain a domain of unknown function DUF1394. We recently showed that CYRI and the DUF1394 can mediate bind...

Full description

Bibliographic Details
Main Authors: Jamie A. Whitelaw, Sergio Lilla, Nikki R. Paul, Loic Fort, Sara Zanivan, Laura M. Machesky
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Communicative & Integrative Biology
Subjects:
gtpase signaling
rac1
cell migration
actin
cancer invasion
Online Access:http://dx.doi.org/10.1080/19420889.2019.1643665

Similar Items

Similar Items