Diagnóstico precoce de histiocitose das células de Langerhans: relato de caso

Langerhans' cells histiocytosis is a disease that belongs to the group of histiocytic disorders and is considered a rare pathology. It results from a proliferation and accumulation of cells of the phagocytic mononuclear system, including Langerhans' cells. This paper reports a case of a 4-...

Full description

Bibliographic Details
Main Authors: Gabriela Saraiva Mangueira, Victoria Boing Trova, André Melo de Faria, Fernanda Vaz Bueno Fagundes
Format: Article
Language:English
Published: Sociedade Brasileira de Pediatria 2024-03-01
Series:Residência Pediátrica
Subjects:
Online Access:https://cdn.publisher.gn1.link/residenciapediatrica.com.br/pdf/v14n1e859.pdf
_version_ 1827287584115523584
author Gabriela Saraiva Mangueira
Victoria Boing Trova
André Melo de Faria
Fernanda Vaz Bueno Fagundes
author_facet Gabriela Saraiva Mangueira
Victoria Boing Trova
André Melo de Faria
Fernanda Vaz Bueno Fagundes
author_sort Gabriela Saraiva Mangueira
collection DOAJ
description Langerhans' cells histiocytosis is a disease that belongs to the group of histiocytic disorders and is considered a rare pathology. It results from a proliferation and accumulation of cells of the phagocytic mononuclear system, including Langerhans' cells. This paper reports a case of a 4-year-old patient who presented a growing, swollen, nodular, depressible and mobile lesion in the right retroauricular region, without pain or phlogistic signs for 6 months, besides erosive and necrotic lesions in the first and second right molars. The confirmatory diagnosis was made by biopsy and immunohistochemistry. This is a study of the medical record, histological evaluations, laboratory and imaging tests of the patient, with the aim of discussing the pathology, making the diagnosis and treatment earlier.
first_indexed 2024-04-24T11:13:49Z
format Article
id doaj.art-4e339359d6ec4dc3add370615cfc1fee
institution Directory Open Access Journal
issn 2236-6814
language English
last_indexed 2024-04-24T11:13:49Z
publishDate 2024-03-01
publisher Sociedade Brasileira de Pediatria
record_format Article
series Residência Pediátrica
spelling doaj.art-4e339359d6ec4dc3add370615cfc1fee2024-04-11T11:58:32ZengSociedade Brasileira de PediatriaResidência Pediátrica2236-68142024-03-0114110.25060/residpediatr-2024.v14n1-859Diagnóstico precoce de histiocitose das células de Langerhans: relato de casoGabriela Saraiva Mangueira0Victoria Boing Trova1André Melo de Faria2Fernanda Vaz Bueno Fagundes3Universidade do Grande Rio, Escola de Ciências da Saúde - Rio de Janeiro - Rio de Janeiro - BrasilUniversidade do Grande Rio, Escola de Ciências da Saúde - Rio de Janeiro - Rio de Janeiro - BrasilUniversidade do Grande Rio, Escola de Ciências da Saúde - Rio de Janeiro - Rio de Janeiro - BrasilUniversidade do Grande Rio, Escola de Ciências da Saúde - Rio de Janeiro - Rio de Janeiro - BrasilLangerhans' cells histiocytosis is a disease that belongs to the group of histiocytic disorders and is considered a rare pathology. It results from a proliferation and accumulation of cells of the phagocytic mononuclear system, including Langerhans' cells. This paper reports a case of a 4-year-old patient who presented a growing, swollen, nodular, depressible and mobile lesion in the right retroauricular region, without pain or phlogistic signs for 6 months, besides erosive and necrotic lesions in the first and second right molars. The confirmatory diagnosis was made by biopsy and immunohistochemistry. This is a study of the medical record, histological evaluations, laboratory and imaging tests of the patient, with the aim of discussing the pathology, making the diagnosis and treatment earlier.https://cdn.publisher.gn1.link/residenciapediatrica.com.br/pdf/v14n1e859.pdfhistiocytosislangerhans cellslangerhans-cellpediatrics
spellingShingle Gabriela Saraiva Mangueira
Victoria Boing Trova
André Melo de Faria
Fernanda Vaz Bueno Fagundes
Diagnóstico precoce de histiocitose das células de Langerhans: relato de caso
Residência Pediátrica
histiocytosis
langerhans cells
langerhans-cell
pediatrics
title Diagnóstico precoce de histiocitose das células de Langerhans: relato de caso
title_full Diagnóstico precoce de histiocitose das células de Langerhans: relato de caso
title_fullStr Diagnóstico precoce de histiocitose das células de Langerhans: relato de caso
title_full_unstemmed Diagnóstico precoce de histiocitose das células de Langerhans: relato de caso
title_short Diagnóstico precoce de histiocitose das células de Langerhans: relato de caso
title_sort diagnostico precoce de histiocitose das celulas de langerhans relato de caso
topic histiocytosis
langerhans cells
langerhans-cell
pediatrics
url https://cdn.publisher.gn1.link/residenciapediatrica.com.br/pdf/v14n1e859.pdf
work_keys_str_mv AT gabrielasaraivamangueira diagnosticoprecocedehistiocitosedascelulasdelangerhansrelatodecaso
AT victoriaboingtrova diagnosticoprecocedehistiocitosedascelulasdelangerhansrelatodecaso
AT andremelodefaria diagnosticoprecocedehistiocitosedascelulasdelangerhansrelatodecaso
AT fernandavazbuenofagundes diagnosticoprecocedehistiocitosedascelulasdelangerhansrelatodecaso