Stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistula
Rectovaginal fistula, which can arise after an injury to the vaginal canal or rectum, is a troublesome obstacle for patients’ everyday life. In most cases, it can be covered with a local flap, but previous radiation therapy increases the recurrence rate, making it especially difficult to cure. As th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical Publishers, Inc.
2021-01-01
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| Series: | Archives of Plastic Surgery |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.5999/aps.2020.01718 |
| _version_ | 1811305517877821440 |
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| author | Mijung Kim Dae Hyun Lew Tai Suk Roh Seung Yong Song |
| author_facet | Mijung Kim Dae Hyun Lew Tai Suk Roh Seung Yong Song |
| author_sort | Mijung Kim |
| collection | DOAJ |
| description | Rectovaginal fistula, which can arise after an injury to the vaginal canal or rectum, is a troublesome obstacle for patients’ everyday life. In most cases, it can be covered with a local flap, but previous radiation therapy increases the recurrence rate, making it especially difficult to cure. As the application of stromal vascular fraction (SVF) obtained from enzymatically digested autologous adipose tissue has become increasingly common, several reports have advocated its effectiveness for the treatment of refractory wounds. In light of the angiogenic, regenerative characteristics of SVF, it was incorporated as a treatment option in two cases of rectovaginal fistula discussed here. As described in this report, irradiated rectovaginal fistulas in rectal cancer patients were successfully treated with SVF injection, and we suggest SVF as a feasible treatment option for cases of rectovaginal fistula that would otherwise be very difficult to cure. |
| first_indexed | 2024-04-13T08:27:50Z |
| format | Article |
| id | doaj.art-4e33bf06ff554eea9d8bf641d744d2fe |
| institution | Directory Open Access Journal |
| issn | 2234-6163 2234-6171 |
| language | English |
| last_indexed | 2024-04-13T08:27:50Z |
| publishDate | 2021-01-01 |
| publisher | Thieme Medical Publishers, Inc. |
| record_format | Article |
| series | Archives of Plastic Surgery |
| spelling | doaj.art-4e33bf06ff554eea9d8bf641d744d2fe2022-12-22T02:54:22ZengThieme Medical Publishers, Inc.Archives of Plastic Surgery2234-61632234-61712021-01-01480112713010.5999/aps.2020.017183823Stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistulaMijung Kim0Dae Hyun Lew1Tai Suk Roh2Seung Yong Song3Department of Plastic and Reconstructive Surgery, Yonsei University College of Medicine, Seoul, KoreaDepartment of Plastic and Reconstructive Surgery, Yonsei University College of Medicine, Seoul, KoreaDepartment of Plastic and Reconstructive Surgery, Yonsei University College of Medicine, Seoul, KoreaDepartment of Plastic and Reconstructive Surgery, Yonsei University College of Medicine, Seoul, KoreaRectovaginal fistula, which can arise after an injury to the vaginal canal or rectum, is a troublesome obstacle for patients’ everyday life. In most cases, it can be covered with a local flap, but previous radiation therapy increases the recurrence rate, making it especially difficult to cure. As the application of stromal vascular fraction (SVF) obtained from enzymatically digested autologous adipose tissue has become increasingly common, several reports have advocated its effectiveness for the treatment of refractory wounds. In light of the angiogenic, regenerative characteristics of SVF, it was incorporated as a treatment option in two cases of rectovaginal fistula discussed here. As described in this report, irradiated rectovaginal fistulas in rectal cancer patients were successfully treated with SVF injection, and we suggest SVF as a feasible treatment option for cases of rectovaginal fistula that would otherwise be very difficult to cure.http://www.thieme-connect.de/DOI/DOI?10.5999/aps.2020.01718rectovaginal fistulafat graftmesenchymal stem cellradiation effect |
| spellingShingle | Mijung Kim Dae Hyun Lew Tai Suk Roh Seung Yong Song Stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistula Archives of Plastic Surgery rectovaginal fistula fat graft mesenchymal stem cell radiation effect |
| title | Stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistula |
| title_full | Stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistula |
| title_fullStr | Stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistula |
| title_full_unstemmed | Stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistula |
| title_short | Stromal vascular fraction injection to treat intractable radiation-induced rectovaginal fistula |
| title_sort | stromal vascular fraction injection to treat intractable radiation induced rectovaginal fistula |
| topic | rectovaginal fistula fat graft mesenchymal stem cell radiation effect |
| url | http://www.thieme-connect.de/DOI/DOI?10.5999/aps.2020.01718 |
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