Expression of C Reactive Protein in Gingival Crevicular Fluid of Patients with Periodontitis Wearing Metal-Ceramic Dental Crowns

Metal-ceramic crowns (MC) have long been considered as gold standard for dental prosthetic restorations. Our study aims to evaluate the influence of MC, with conventional technology used for the framework, on the periodontal parameters and levels of C reactive protein, an inflammatory marker, in gin...

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Main Authors: Alina-Ramona Dimofte, Dorin Nicolae Gheorghe, Dora Maria Popescu, Ioana Mitruț, Petre Costin Mărășescu, Horia Octavian Manolea, Mihail Virgil Boldeanu, Petra Şurlin
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Applied Sciences
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Online Access:https://www.mdpi.com/2076-3417/13/19/10993
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author Alina-Ramona Dimofte
Dorin Nicolae Gheorghe
Dora Maria Popescu
Ioana Mitruț
Petre Costin Mărășescu
Horia Octavian Manolea
Mihail Virgil Boldeanu
Petra Şurlin
author_facet Alina-Ramona Dimofte
Dorin Nicolae Gheorghe
Dora Maria Popescu
Ioana Mitruț
Petre Costin Mărășescu
Horia Octavian Manolea
Mihail Virgil Boldeanu
Petra Şurlin
author_sort Alina-Ramona Dimofte
collection DOAJ
description Metal-ceramic crowns (MC) have long been considered as gold standard for dental prosthetic restorations. Our study aims to evaluate the influence of MC, with conventional technology used for the framework, on the periodontal parameters and levels of C reactive protein, an inflammatory marker, in gingival crevicular fluid in patients diagnosed with periodontitis. Two groups were established: the test group T-28 teeth from the lateral area wearing a MC crown and the control group C-28 teeth without any wearing. These parameters were evaluated: probing depth, Gingival Index, and longevity of crowns. The quantitative assessment through enzyme-linked immunosorbent assay of the targeted pro-inflammatory mediator was performed. There is a difference statistically significant between the groups T and C regarding the marker’s levels and gingival index, a very strong correlation between these levels and probing depth and a strong correlation between longevity and Gingival Index. Periodontal clinical parameters are more pronounced the longer the time elapsed since the application of the crowns. Expression of C reactive protein is higher in the presence of MC crowns.
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spelling doaj.art-4e34743ab5e14ecaa538f4652f5681392023-11-19T14:07:05ZengMDPI AGApplied Sciences2076-34172023-10-0113191099310.3390/app131910993Expression of C Reactive Protein in Gingival Crevicular Fluid of Patients with Periodontitis Wearing Metal-Ceramic Dental CrownsAlina-Ramona Dimofte0Dorin Nicolae Gheorghe1Dora Maria Popescu2Ioana Mitruț3Petre Costin Mărășescu4Horia Octavian Manolea5Mihail Virgil Boldeanu6Petra Şurlin7Doctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaResearch Center of Periodontal-Systemic Implications, Department of Periodontology, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaResearch Center of Periodontal-Systemic Implications, Department of Periodontology, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Dental Prosthesis Technology, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Dental Prosthesis Technology, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Dental Materials, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Immunology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaResearch Center of Periodontal-Systemic Implications, Department of Periodontology, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaMetal-ceramic crowns (MC) have long been considered as gold standard for dental prosthetic restorations. Our study aims to evaluate the influence of MC, with conventional technology used for the framework, on the periodontal parameters and levels of C reactive protein, an inflammatory marker, in gingival crevicular fluid in patients diagnosed with periodontitis. Two groups were established: the test group T-28 teeth from the lateral area wearing a MC crown and the control group C-28 teeth without any wearing. These parameters were evaluated: probing depth, Gingival Index, and longevity of crowns. The quantitative assessment through enzyme-linked immunosorbent assay of the targeted pro-inflammatory mediator was performed. There is a difference statistically significant between the groups T and C regarding the marker’s levels and gingival index, a very strong correlation between these levels and probing depth and a strong correlation between longevity and Gingival Index. Periodontal clinical parameters are more pronounced the longer the time elapsed since the application of the crowns. Expression of C reactive protein is higher in the presence of MC crowns.https://www.mdpi.com/2076-3417/13/19/10993metal-ceramic crownperiodontitisgingival crevicular fluid
spellingShingle Alina-Ramona Dimofte
Dorin Nicolae Gheorghe
Dora Maria Popescu
Ioana Mitruț
Petre Costin Mărășescu
Horia Octavian Manolea
Mihail Virgil Boldeanu
Petra Şurlin
Expression of C Reactive Protein in Gingival Crevicular Fluid of Patients with Periodontitis Wearing Metal-Ceramic Dental Crowns
Applied Sciences
metal-ceramic crown
periodontitis
gingival crevicular fluid
title Expression of C Reactive Protein in Gingival Crevicular Fluid of Patients with Periodontitis Wearing Metal-Ceramic Dental Crowns
title_full Expression of C Reactive Protein in Gingival Crevicular Fluid of Patients with Periodontitis Wearing Metal-Ceramic Dental Crowns
title_fullStr Expression of C Reactive Protein in Gingival Crevicular Fluid of Patients with Periodontitis Wearing Metal-Ceramic Dental Crowns
title_full_unstemmed Expression of C Reactive Protein in Gingival Crevicular Fluid of Patients with Periodontitis Wearing Metal-Ceramic Dental Crowns
title_short Expression of C Reactive Protein in Gingival Crevicular Fluid of Patients with Periodontitis Wearing Metal-Ceramic Dental Crowns
title_sort expression of c reactive protein in gingival crevicular fluid of patients with periodontitis wearing metal ceramic dental crowns
topic metal-ceramic crown
periodontitis
gingival crevicular fluid
url https://www.mdpi.com/2076-3417/13/19/10993
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