Comparison of the Effect of Preoperative Skin Prepartion with Povidone-Iodine and Chlorhexidine-Gluconate on Surgical Site Infection in Laparotomy Patients
Background and Aim: Surgical site infection (SSI) is one of the most common health-care associated infections. Using proper antiseptic solutions for preoperative surgical site skin preparation (skin prep) is one of the methods to reduce SSIs. The purpose of this study was to compare the effect of pr...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | fas |
| Published: |
Tehran University of Medical Sciences
2022-03-01
|
| Series: | پیاورد سلامت |
| Subjects: | |
| Online Access: | http://payavard.tums.ac.ir/article-1-7275-en.pdf |
| _version_ | 1797823077820661760 |
|---|---|
| author | Fardin Amiri Arash Khajehvand Sedigheh Hannani Nemamali Azadi |
| author_facet | Fardin Amiri Arash Khajehvand Sedigheh Hannani Nemamali Azadi |
| author_sort | Fardin Amiri |
| collection | DOAJ |
| description | Background and Aim: Surgical site infection (SSI) is one of the most common health-care associated infections. Using proper antiseptic solutions for preoperative surgical site skin preparation (skin prep) is one of the methods to reduce SSIs. The purpose of this study was to compare the effect of preoperative surgical site skin preparation with povidone-iodine and chlorhexidine-gluconate on the rate of SSI in laparotomy patients.
Materials and Methods: A total of 70 Laparotomy surgery patients who referred to Firoozgar hospital in Tehran from May to September of 2021 were included in this clinical trial. Patients were randomly allocated into two groups which were treated with povidone-iodine(PVI) or chlorhexidine-gluconate (CHG) for surgical site skin prep. Skin prep was done with standard rotational method in two steps by the researcher for each group by using of PVI and CHG. SSI incidence was assessed by a researcher-made check list and also over post-surgical follow up visits by the surgeon. We used Fischer’s exact test, t-test, Chi-square and Cochrane’s Q-test to analyze the collected data.
Results: SSI was seen in five patients (14.29%) of PVI group and one patient (2.86%) of CHG group. Although the SSI incidence in PVI group was 5.54 times more than CHG group, still the difference wasn’t statistically significant (P=0.198). Comparing the incidence of SSI’s in 24 hours after surgery (0%) and 30 days after surgery (8.57%) in both groups revealed that using these antiseptics for skin prep was effective in preventing SSI (P<0.001). SSI incidence was also associated with two days of patient’s hospital admission time (P=0.001).
Conclusion: The result of this study revealed that the occurrence of SSI in PVI group was 5.54 times more than CHG group. However, the difference was not statistically significant. So both of these antiseptics can be used for surgical site skin prep. |
| first_indexed | 2024-03-13T10:18:41Z |
| format | Article |
| id | doaj.art-4e34d97a8bc8405094826ade4ed1ec46 |
| institution | Directory Open Access Journal |
| issn | 1735-8132 2008-2665 |
| language | fas |
| last_indexed | 2024-03-13T10:18:41Z |
| publishDate | 2022-03-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | پیاورد سلامت |
| spelling | doaj.art-4e34d97a8bc8405094826ade4ed1ec462023-05-21T05:35:17ZfasTehran University of Medical Sciencesپیاورد سلامت1735-81322008-26652022-03-01165412421Comparison of the Effect of Preoperative Skin Prepartion with Povidone-Iodine and Chlorhexidine-Gluconate on Surgical Site Infection in Laparotomy PatientsFardin Amiri0Arash Khajehvand1Sedigheh Hannani2Nemamali Azadi3 Assistant Professor, Department of Operating Room, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran Master of Sciences Student in Operating Room, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran Instructor, Department of Operating Room, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran Associate Professor, Department of Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran, Iran Background and Aim: Surgical site infection (SSI) is one of the most common health-care associated infections. Using proper antiseptic solutions for preoperative surgical site skin preparation (skin prep) is one of the methods to reduce SSIs. The purpose of this study was to compare the effect of preoperative surgical site skin preparation with povidone-iodine and chlorhexidine-gluconate on the rate of SSI in laparotomy patients. Materials and Methods: A total of 70 Laparotomy surgery patients who referred to Firoozgar hospital in Tehran from May to September of 2021 were included in this clinical trial. Patients were randomly allocated into two groups which were treated with povidone-iodine(PVI) or chlorhexidine-gluconate (CHG) for surgical site skin prep. Skin prep was done with standard rotational method in two steps by the researcher for each group by using of PVI and CHG. SSI incidence was assessed by a researcher-made check list and also over post-surgical follow up visits by the surgeon. We used Fischer’s exact test, t-test, Chi-square and Cochrane’s Q-test to analyze the collected data. Results: SSI was seen in five patients (14.29%) of PVI group and one patient (2.86%) of CHG group. Although the SSI incidence in PVI group was 5.54 times more than CHG group, still the difference wasn’t statistically significant (P=0.198). Comparing the incidence of SSI’s in 24 hours after surgery (0%) and 30 days after surgery (8.57%) in both groups revealed that using these antiseptics for skin prep was effective in preventing SSI (P<0.001). SSI incidence was also associated with two days of patient’s hospital admission time (P=0.001). Conclusion: The result of this study revealed that the occurrence of SSI in PVI group was 5.54 times more than CHG group. However, the difference was not statistically significant. So both of these antiseptics can be used for surgical site skin prep.http://payavard.tums.ac.ir/article-1-7275-en.pdfantisepticpovidone-iodinechlorhexidine-gluconatesurgical site infection |
| spellingShingle | Fardin Amiri Arash Khajehvand Sedigheh Hannani Nemamali Azadi Comparison of the Effect of Preoperative Skin Prepartion with Povidone-Iodine and Chlorhexidine-Gluconate on Surgical Site Infection in Laparotomy Patients پیاورد سلامت antiseptic povidone-iodine chlorhexidine-gluconate surgical site infection |
| title | Comparison of the Effect of Preoperative Skin Prepartion with Povidone-Iodine and Chlorhexidine-Gluconate on Surgical Site Infection in Laparotomy Patients |
| title_full | Comparison of the Effect of Preoperative Skin Prepartion with Povidone-Iodine and Chlorhexidine-Gluconate on Surgical Site Infection in Laparotomy Patients |
| title_fullStr | Comparison of the Effect of Preoperative Skin Prepartion with Povidone-Iodine and Chlorhexidine-Gluconate on Surgical Site Infection in Laparotomy Patients |
| title_full_unstemmed | Comparison of the Effect of Preoperative Skin Prepartion with Povidone-Iodine and Chlorhexidine-Gluconate on Surgical Site Infection in Laparotomy Patients |
| title_short | Comparison of the Effect of Preoperative Skin Prepartion with Povidone-Iodine and Chlorhexidine-Gluconate on Surgical Site Infection in Laparotomy Patients |
| title_sort | comparison of the effect of preoperative skin prepartion with povidone iodine and chlorhexidine gluconate on surgical site infection in laparotomy patients |
| topic | antiseptic povidone-iodine chlorhexidine-gluconate surgical site infection |
| url | http://payavard.tums.ac.ir/article-1-7275-en.pdf |
| work_keys_str_mv | AT fardinamiri comparisonoftheeffectofpreoperativeskinprepartionwithpovidoneiodineandchlorhexidinegluconateonsurgicalsiteinfectioninlaparotomypatients AT arashkhajehvand comparisonoftheeffectofpreoperativeskinprepartionwithpovidoneiodineandchlorhexidinegluconateonsurgicalsiteinfectioninlaparotomypatients AT sedighehhannani comparisonoftheeffectofpreoperativeskinprepartionwithpovidoneiodineandchlorhexidinegluconateonsurgicalsiteinfectioninlaparotomypatients AT nemamaliazadi comparisonoftheeffectofpreoperativeskinprepartionwithpovidoneiodineandchlorhexidinegluconateonsurgicalsiteinfectioninlaparotomypatients |