Pharmacokinetics of DA-6886, A New 5-HT<sub>4</sub> Receptor Agonist, in Rats

Pharmacokinetics of DA-6886, A New 5-HT<sub>4</sub> Receptor Agonist, in Rats

DA-6886 is a novel serotonin (5-hydroxytrypamine [5-HT]) receptor 4 agonist for the potential treatment of constipation-predominant irritable bowel syndrome. The purpose of this study was to validate the quantitative assay of DA-6886 in rat plasma and to evaluate the pharmacokinetics and tissue dist...

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Bibliographic Details
Main Authors:	Dae Young Lee, Hee Eun Kang
Format:	Article
Language:	English
Published:	MDPI AG 2022-03-01
Series:	Pharmaceutics
Subjects:	DA-6886 5-HT<sub>4</sub> receptor agonist LC–MS/MS pharmacokinetics dose-dependency
Online Access:	https://www.mdpi.com/1999-4923/14/4/702

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